Health Information

Cycloserine

Drug Information

Cycloserine is a broad-spectrum antibiotic used to treat tuberculosis. It is used rarely for treating noninfectious diseases.

Common brand names:

Seromycin

Summary of Interactions with Vitamins, Herbs, & Foods

Reference What Are Nutrient Interactions

Types of interactions: Beneficial Adverse Check

Replenish Depleted Nutrients

Reference Vitamin K

Many antibiotics taken by mouth, including cycloserine, may kill friendly bacteria in the large intestine that produce vitamin K.¹ With short-term (a few weeks or less) antibiotic use, the actions on vitamin K are usually mild and cause no problems. After antibiotic therapy is completed, vitamin K activity returns to normal.
Reference Calcium

Cycloserine may interfere with calcium and magnesium absorption.² The clinical significance of these interactions is unclear.

Cycloserine may interfere with the absorption and/or activity of folic acid, vitamin B6, and vitamin B12.³ ^{, 4} The clinical importance of this interaction is unclear.

The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Reference Folic Acid

Cycloserine may interfere with calcium and magnesium absorption.⁵ The clinical significance of these interactions is unclear.

Cycloserine may interfere with the absorption and/or activity of folic acid, vitamin B6, and vitamin B12.⁶ ^{, 7} The clinical importance of this interaction is unclear.

The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Reference Magnesium

Cycloserine may interfere with calcium and magnesium absorption.⁸ The clinical significance of these interactions is unclear.

Cycloserine may interfere with the absorption and/or activity of folic acid, vitamin B6, and vitamin B12.⁹ ^{, 10} The clinical importance of this interaction is unclear.

The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Reference Vitamin B12

Cycloserine may interfere with calcium and magnesium absorption.¹¹ The clinical significance of these interactions is unclear.

Cycloserine may interfere with the absorption and/or activity of folic acid, vitamin B6, and vitamin B12.¹² ^{, 13} The clinical importance of this interaction is unclear.

The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Reference Vitamin B6

Cycloserine may interfere with calcium and magnesium absorption.¹⁴ The clinical significance of these interactions is unclear.

Cycloserine may interfere with the absorption and/or activity of folic acid, vitamin B6, and vitamin B12.¹⁵ ^{, 16} The clinical importance of this interaction is unclear.

The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.

Reduce Side Effects

none

Support Medicine

none

Reduces Effectiveness

none

Potential Negative Interaction

none

Explanation Required

none

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

References

1. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

2. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

3. Roe D, Campbell T, eds. Drugs and Nutrients: The Interactive Effects. New York: Marcel Decker, 1984, 288–9, 505–23.

4. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

5. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

6. Roe D, Campbell T, eds. Drugs and Nutrients: The Interactive Effects. New York: Marcel Decker, 1984, 288–9, 505–23.

7. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

8. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

9. Roe D, Campbell T, eds. Drugs and Nutrients: The Interactive Effects. New York: Marcel Decker, 1984, 288–9, 505–23.

10. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

11. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

12. Roe D, Campbell T, eds. Drugs and Nutrients: The Interactive Effects. New York: Marcel Decker, 1984, 288–9, 505–23.

13. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

14. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

15. Roe D, Campbell T, eds. Drugs and Nutrients: The Interactive Effects. New York: Marcel Decker, 1984, 288–9, 505–23.

16. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

Last Review: 11-07-2012

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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2013.

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