Shelled Hemp Seed
Parts Used & Where Grown
Hemp is a form of the same plant as marijuana that generally has much lower levels of the psychoactive cannabinoid compounds. The seed and seed oil have probably been used for food, cooking, and lamp oil in Asia and North Africa for millennia. Hemp is believed to come from China. The nutty seeds normally have a hard shell which has to be removed to make it edible. Today, in order to be legal in most countries, the seeds must be treated so that they cannot be planted and grown.
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3 Stars Reliable and relatively consistent scientific data showing a substantial health benefit.
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1 Star For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
This supplement has been used in connection with the following health conditions:
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Shelled hemp seed or its oil may theoretically be useful for people with atherosclerosis due to its essential fatty acid content.
Though it has not been studied, Reference shelled hemp seed or its oil may theoretically be useful for people with atherosclerosis due to its content of essential fatty acids.3
Attention Deficit–Hyperactivity Disorder
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Theoretically shelled hemp seed may be useful for people with ADHD due to its essential fatty acid content.
Though it has not been studied, theoretically Reference shelled hemp seed may be useful for people with ADHD due to its content of essential fatty acids.4 , 5
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Theoretically shelled hemp seed or its oil may be useful for people with eczema due to its essential fatty acid content.
Though it has not been studied, theoretically Reference shelled hemp seed or its oil may be useful for people with eczema due to its content of essential fatty acids.6
Traditional Use (May Not Be Supported by Scientific Studies)
Hemp is known from archeological and historical records to have been used for a very long time for making fiber for clothing and ropes. The edible seeds and oil expressed from the seeds are noted in ancient Chinese medicine for their medicinal effects as well. Known as huo ma ren (literally “fire hemp seed”), hemp seed is used primarily for alleviating constipation as a bulk-forming laxative.1 Hemp is also mentioned in ancient Egyptian medical texts such as the Ebers papyrus as well as other places for use in making rope.2
How It Works
How It Works
Hemp seeds contain oil that is relatively rich in essential fatty acids. In particular, hemp oil is a source of both the omega-3 fatty acid alpha-linolenic acid (ALA) and the omega-6 fatty acid gamma-linolenic acid (GLA). A tablespoon of seeds generally contains 3 to 4 grams of total fat, of which 70% are polyunsaturated fats and as much as 15 to 20% are ALA.7 GLA content is generally much lower at roughly 2 to 5%. ALA and GLA and other plants that contain one or both of these substances, such as Reference flax, Reference borage, Reference evening primrose, and black currant, are known or strongly believed to have benefits for a variety of inflammatory conditions, atherosclerosis, and some neurological problems. However, the benefits of hemp seed for any of these issues has not been studied. Hemp also contains natural Reference vitamin E and a significant amount of protein.8
An unidentified compound or compounds from an extract of hemp seeds has been shown to promote memory, learning, and immune function in mice.9 , 10 It is believed to act by stimulating a brain enzyme known as calcineurin.
Hemp seeds contain cannabinols such as delta-9-tetrahydrocannabinol (THC), the psychoactive compounds found in marijuana leaves, flowers, and seeds. The levels are generally significantly lower than those found in marijuana products, and most tests have found that volunteers fed even large amounts of shelled hemp seed or oil do not have psychological effects and do not have positive urine tests for marijuana.11 , 12 However, some reports have found that some people can develop sufficient levels of THC metabolites in their urine that they would be considered to have smoked marijuana.13
How to Use It
Typically 1 tablespoon (15 grams) of shelled hemp seed is taken twice per day.
Interactions with Supplements, Foods, & Other Compounds
As the oils in hemp seed are known to inhibit platelets, anyone taking hemp seed oil with anticoagulant drugs should be aware that there is a theoretical possibility that bleeding could occur.
Interactions with Medicines
For most people there are no side effects, except sometimes loosening of the stool. However, some people may experience hallucinations or euphoria if they are particularly sensitive to THC or if they happen to use a brand that has somewhat higher THC levels.
1. Chen JK, Chen TT. Chinese Medical Herbology and Pharmacology. City of Industry, CA: Art of Medicine Press, Inc., 2003.
2. Nunn JF. Ancient Egyptian Medicine. Norman: University of Oklahoma Press, 1996:156.
3. Fitzsimmons S. Hemp seed oil: Fountain of youth? Br J Phytother 1998;5:90–6.
4. Stevens LJ, Zentall SS, Deck JL, et al. Essential fatty acid metabolism in boys with attention-deficit hyperactivity disorder. Am J Clin Nutr 1995;62:761–8
5. Fitzsimmons S. Hemp seed oil: Fountain of youth? Br J Phytother 1998;5:90–6.
6. Fitzsimmons S. Hemp seed oil: Fountain of youth? Br J Phytother 1998;5:90–6.
7. Fitzsimmons S. Hemp seed oil: Fountain of youth? Br J Phytother 1998;5:90–6.
8. Odani S, Odani S. Isolation and primary structure of a methionine- and cysteine-rich seed protein of Cannabis sativa. Biosci Biotechnol Biochem 1998;62:650–4.
9. Luo J, Yin JH, Wei Q. The effect of calcineurin activator, extracted from Chinese herbal medicine, on memory and immunity in mice. Pharmacol Biochem Behav 2003;75:749–54.
10. Luo J, Yin JH, Wu HZ, Wei Q. Extract from fructus cannabis activating calcineurin improved learning and memory in mice with chemical drug-induced dysmnesia. Acta Pharmacol Sin 2003;24:1137–42.
11. Leson G, Pless P, Grotenhermen F, et al. Evaluating the impact of hemp food consumption on workplace drug tests. J Anal Toxicol 2001;25:691–8.
12. Steinagle GC, Upfal M. Concentration of marijuana metabolites in the urine after ingestion of hemp seed tea. J Occup Environ Med 1999;41:510–3.
13. Fortner N, Fogerson R, Lindman D, et al. Marijuana-positive urine test results from consumption of hemp seeds in food products. J Anal Toxicol 1997;21:476–81.
Last Review: 11-07-2012
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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2013.