Progestin for Endometriosis

Reference Progestin Opens New Window shrinks endometriosis growths—which are also called implants—and reduces pain for most women.

Progestin is similar to the body's hormone Reference progesterone Opens New Window. Taking progestin creates levels in the body similar to pregnancy. This stops monthly growth of the uterine lining (Reference endometrium Opens New Window) and Reference endometriosis Opens New Window implants elsewhere in the body. Progestin also reduces Reference estrogen Opens New Window production, which stops Reference ovulation Opens New Window and menstrual periods in most women.

The Reference levonorgestrel (LNg) intrauterine device (IUD) is used to treat endometriosis. It releases a lower daily dose of levonorgestrel, a form of progestin, directly into the uterus. This causes fewer side effects than high-dose progestin pills or injections. In addition to reducing cramping and heavy menstrual bleeding, the LNg IUD is a highly effective method of birth control.

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