Danazol for Endometriosis
Why It Is Used
Danazol is occasionally used to treat endometriosis, usually when all other hormone therapies have not helped. Danazol can:
- Relieve pain.
- Prevent endometriosis from getting worse.
- Reduce the size of endometriosis implants.
- Be used to shrink implants before surgery, which can help prevent internal scarring from the surgery.
Danazol is not widely used to treat endometriosis and other estrogen-related conditions, because it can cause serious side effects. Because of these serious side effects, such as increased Reference cholesterol Opens New Window levels, danazol use is limited to 6 to 9 months at a time. Danazol may not be appropriate if you already have a high risk for developing increased cholesterol levels or liver disease.
Reasons not to use danazol include:
- Undiagnosed abnormal vaginal bleeding.
- Chronic liver, kidney, or heart disease, which can become worse with danazol therapy.
- Pregnancy or possibility of pregnancy during treatment (danazol can harm a fetus).
- Inherited disorder of skin pigment (porphyria).
|By:||Reference Healthwise Staff||Last Revised: May 14, 2012|
|Medical Review:||Reference Adam Husney, MD - Family Medicine
Reference Kirtly Jones, MD - Obstetrics and Gynecology