Health Information
Antidepressants for Urinary Incontinence
How It Works
Duloxetine is an antidepressant called a "selective serotonin and norepinephrine reuptake inhibitor." It changes how the brain uses certain brain chemicals. How it helps with bladder control is not yet known.
Imipramine is a tricyclic antidepressant, but it has anticholinergic side effects. This means that it relaxes the smooth muscle of the bladder. It also causes the muscles at the bladder neck to contract.
| By: | Reference Healthwise Staff | Last Revised: September 11, 2012 |
| Medical Review: | Reference E. Gregory Thompson, MD - Internal Medicine
Reference Avery L. Seifert, MD - Urology |
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