Health Information
Lymph Node Biopsy
How It Is Done
Fine-needle aspiration biopsy
A needle biopsy of a lymph node near the skin is usually done by a Reference hematologist Opens New Window, a Reference radiologist Opens New Window, or a Reference general surgeon Opens New Window. A needle biopsy of a lymph node deeper within the body is usually done by a radiologist using a Reference CT scan Opens New Window or Reference ultrasound to help guide the needle. The biopsy may be done in a surgery clinic or the hospital.
You will need to take off all or most of your clothes (you may be allowed to keep on your underwear if it does not interfere with the biopsy). You will be given a cloth or paper covering to use during the biopsy.
Your doctor numbs the area of your breast where the needle will be inserted. Once the area is numb, the needle is put through the skin and into the lymph node. The biopsy sample is sent to a lab to be looked at under a microscope. You must lie still while the biopsy is done.
The needle is then removed. Pressure is put on the needle site to stop any bleeding. A bandage is put on. A fine-needle aspiration biopsy takes about 5 to 15 minutes.
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Core needle biopsy
A core needle biopsy is usually done by a general surgeon or radiologist.
You will need to take off all or most of your clothes (you may be allowed to keep on your underwear if it does not interfere with the biopsy). You will be given a cloth or paper covering to use during the biopsy.
Your doctor numbs the area of your breast where the needle will be inserted. Once the area is numb, a small cut is made in the skin. A needle with a special tip is put through the skin and into the lymph node. You must lie still while the biopsy is done.
The needle is then removed. Pressure is put on the needle site to stop any bleeding. A bandage is put on. A core needle biopsy takes about 20 minutes.
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Open biopsy and lymph node dissection
An open biopsy of a lymph node is done by a surgeon. For a lymph node near the surface of the skin, the biopsy site is numbed with local anesthetic. For a lymph node deeper in the body or for lymph node dissection, you may have general anesthesia.
You will need to take off all or most of your clothes (you may be allowed to keep on your underwear if it does not interfere with the biopsy). You will be given a cloth or paper covering to use during the biopsy. Your hands may be at your sides or raised above your head (depending on which position makes it easiest to find the lymph node).
You will lie on an examining table and the skin over the biopsy site will be cleaned with a special soap. The area is covered with a sterile sheet. A small cut will be made so the whole lymph node or a slice of it can be taken out.
Stitches are used to close the skin, and a bandage is put on. You will be taken to a recovery room until you are fully awake. You can usually return to your normal activities the next day.
An open biopsy usually takes from 30 to 60 minutes. If you have had a lymph node dissection to remove cancer, the surgery may take longer.
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| By: | Reference Healthwise Staff | Last Revised: Reference March 29, 2011 |
| Medical Review: | Reference Sarah Marshall, MD - Family Medicine
Reference C. Dale Mercer, MD, FRCSC, FACS - General Surgery |
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This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Reference Terms of Use. Reference How this information was developed to help you make better health decisions.

