Health Information
Tricyclic and Tetracyclic Antidepressants for Depression
Examples
Tricyclic antidepressants (TCAs)
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Heterocyclic antidepressants
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These are older (first-generation) antidepressants. They generally have more side effects than newer (second-generation) antidepressants such as Reference serotonin reuptake inhibitors (SSRIs) and Reference other second-generation antidepressants such as bupropion (Wellbutrin, Wellbutrin SR) and duloxetine (Cymbalta).
| By: | Reference Healthwise Staff | Last Revised: May 14, 2012 |
| Medical Review: | Reference Kathleen Romito, MD - Family Medicine
Reference Lisa S. Weinstock, MD - Psychiatry |
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