Health Information
Leucovorin
How Well It Works
Most of the complications and side effects of methotrexate can be either prevented or treated by using leucovorin, which is usually given 24 hours after the methotrexate is given.
Leucovorin enhances the binding of fluorouracil (5-FU) and prolongs the life span of 5-FU, increasing the anticancer effect.Reference 1
| By: | Reference Healthwise Staff | Last Revised: August 27, 2012 |
| Medical Review: | Reference E. Gregory Thompson, MD - Internal Medicine
Reference Kenneth Bark, MD - Surgery, Colon and Rectal |
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