Main content

    Health Information

    Alpha-Blocker Medicines for Prostatitis

    Alpha-Blocker Medicines for Prostatitis


    Generic Name Brand Name
    alfuzosin Uroxatral
    doxazosin Cardura
    silodosin Rapaflo
    tamsulosin Flomax
    terazosin Hytrin

    These medicines are available in pill form. A low dose is used at first, then the dosage is gradually increased until the medicine has the greatest effect on reducing symptoms with minimal side effects.

    How It Works

    These medicines relax the muscles in the prostate and at the base of the bladder. This reduces muscle tightness and spasms that may prevent normal urine flow.

    Why It Is Used

    These medicines may be used to treat symptoms of chronic prostatitis/pelvic pain syndrome, noninflammatory, a type of prostatitis , when muscle tightness and spasms are suspected to be the cause of symptoms and pain.

    How Well It Works

    Most men who take alpha-blockers for prostatitis have fewer symptoms, but it takes awhile for the medicine to give results. Alpha-blockers work best in men who haven't already tried many different kinds of medicines for prostatitis and who have moderate to severe symptoms. 1

    Taking an antibiotic and an alpha-blocker together helps to improve symptoms of chronic prostatitis and chronic pelvic pain better than either medicine alone. 2

    Side Effects

    Alpha-blockers can reduce blood pressure to less than normal. This can result in lightheadedness, especially when you stand up abruptly after sitting or lying down (postural hypotension).

    See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

    What To Think About

    Because this medicine can cause lightheadedness, it may be given at night and started at a low dose that will be gradually increased.

    Complete the new medication information form (PDF) (What is a PDF document?) to help you understand this medication.



    1. Nickel JC (2012). Prostatitis and related conditions, orchitis, and epididymitis. In AJ Wein et al., eds., Campbell-Walsh Urology, 10th ed., vol. 1, pp. 327?356. Philadelphia: Saunders.
    2. Anothaisintawee T, et al. (2011). Management of chronic prostatitis/chronic pelvic pain syndrome. JAMA, 305(1): 78?86.


    By Healthwise Staff
    E. Gregory Thompson, MD - Internal Medicine
    Christopher G. Wood, MD, FACS - Urology, Oncology
    Last Revised November 11, 2013

    This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

    1995-2014 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.