Nephrotic syndrome is a rare kidney disorder that causes high
levels of protein in the urine (proteinuria) and low levels of protein in the
blood. It may cause high cholesterol and swelling around the eyes, legs, and
Symptoms of nephrotic syndrome include loss of appetite,
unexpected weight gain, abdominal (belly) pain, and weakness.
causes of nephrotic syndrome include kidney diseases as well as other diseases
and conditions that affect the kidneys, including diabetes, systemic lupus
erythematosus (SLE), and hepatitis C. Allergic reactions to insect bites,
poisonous plants, and medicines can also lead to nephrotic syndrome.
Nephrotic syndrome can affect both adults and children. It can often be
cured by removing or treating the cause (for instance, stopping use of a
medicine). If the cause is not treatable or is not known, medicines may be
used to reduce the symptoms of nephrotic syndrome. If the problem causing
nephrotic syndrome is not corrected, the disorder can progress to kidney
Anne C. Poinier, MD - Internal Medicine & Tushar J. Vachharajani, MD, FASN, FACP - Nephrology
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