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    Glycoprotein IIb/IIIa Inhibitors for Heart Attack and Unstable Angina

    Glycoprotein IIb/IIIa Inhibitors for Heart Attack and Unstable Angina

    Examples

    Generic Name Brand Name
    abciximab ReoPro
    eptifibatide Integrilin
    tirofiban Aggrastat

    How It Works

    These medicines prevent the formation of blood clots. They can help prevent blood clots in the coronary arteries after a heart attack.

    Why It Is Used

    Glycoprotein IIb/IIIa inhibitors might be used with angioplasty after a heart attack. But they are not used for everyone.

    How Well It Works

    Glycoprotein IIb/IIIa inhibitors may help certain people who have angioplasty after a heart attack, such as people who are at high risk for serious blood clots. 1

    Side Effects

    Glycoprotein IIb/IIIa inhibitors are given in the hospital. So a person is watched closely for any side effects.

    Bleeding inside the body is the most common side effect.

    See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

    What To Think About

    Glycoprotein IIb/IIIa inhibitors are only used in the hospital.

    Complete the new medication information form (PDF) (What is a PDF document?) to help you understand this medication.

    References

    Citations

    1. O'Gara PT, et al. (2013). 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: Executive summary. A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation, 127(4): e362?e425.

    Credits

    By Healthwise Staff
    Rakesh K. Pai, MD, FACC - Cardiology, Electrophysiology
    Stephen Fort, MD, MRCP, FRCPC - Interventional Cardiology
    Last Revised February 13, 2013

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