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    Types of Peptic Ulcers

    Types of Peptic Ulcers



    Topic Overview

    There are two different types of Reference peptic ulcers Opens New Window. They are:

    • Gastric ulcers, which form in the lining of the stomach.
    • Duodenal ulcers, which form in the upper small intestine.

    Both types of peptic ulcers are most commonly caused either by infection with Reference Helicobacter pylori (H. pylori) bacteria Opens New Window or by frequent use of Reference nonsteroidal anti-inflammatory drugs (NSAIDs) Opens New Window.

    The symptoms of gastric ulcers and duodenal ulcers are similar, except for when pain occurs.

    • Pain from a gastric ulcer often occurs when food is still in the stomach, shortly after eating.
    • Pain from a duodenal ulcer often occurs when the stomach is empty, several hours after eating, and may improve after eating. Pain also may wake you in the middle of the night.

    Symptoms alone cannot be used to distinguish a gastric ulcer from a duodenal ulcer. Tests such as an Reference endoscopy Opens New Window or an Reference upper gastrointestinal (UGI) series Opens New Window may need to be used to find out the location of an ulcer.

    Gastric ulcers often heal more slowly than duodenal ulcers. A gastric ulcer that does not respond to treatment could be cancer. Your doctor will most likely recommend a Reference biopsy Opens New Window of a gastric ulcer before beginning treatment. The biopsy will make sure there is no cancer hiding in the ulcer.



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