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    Azathioprine

    Topic Contents

    Azathioprine

    Drug Information

    Azathioprine is used to prevent organ rejection following kidney transplant and to treat severe cases of rheumatoid arthritis .

    Common brand names:

    Azasan, Imuran

    Summary of Interactions with Vitamins, Herbs, & Foods

    Types of interactions: Beneficial Adverse Check

    Replenish Depleted Nutrients

    • Folic Acid

      People receiving dialysis for kidney failure often have low blood levels of folic acid. However, folic acid blood levels should return to normal following kidney transplant. A preliminary study of people taking azathioprine to prevent organ rejection revealed that blood levels of folic acid remained well below those of individuals not taking the drug. The highest blood folic acid level was observed in an individual who had not taken azathioprine for two years.1 Controlled studies are needed to determine whether people taking azathioprine should supplement with folic acid.

    Reduce Side Effects

    • none

    Support Medicine

    • none

    Reduces Effectiveness

    • none

    Potential Negative Interaction

    • none

    Explanation Required

    • none

    The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers? package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

    References

    1. Zazgornik J, Druml W, Balcke P, et al. Diminished serum folic acid levels in renal transplant recipients. Clin Nephrol 1982;18:306?10.

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