Discusses cyclophosphamide, medicine used to treat cancer and for some transplant patients. Includes generic and brand name cyclophosphamide (Cytoxan). Covers why it is used, how well it works, and possible side effects.
How It Works
Cyclophosphamide is an alkylating agent
and is related to mustard gas. It causes cell death by interfering with the way
genetic material (DNA) in the cell multiplies.
available as an intravenous (IV) medicine and as tablets for oral use in 25 mg
and 50 mg. The type and extent of a disease and your body size determine the
exact dose and schedule of administering this medicine.
Why It Is Used
Cyclophosphamide is used to treat many
forms of cancer, including:
Cyclophosphamide is also used to treat other diseases, such
Cyclophosphamide is often used before a
bone marrow transplant or after another type of
transplant, such as a kidney or liver transplant.
How Well It Works
Cyclophosphamide treats many forms of
cancer. It is usually combined with other chemotherapy medicines but may be
Side effects with cyclophosphamide may
Decreased white blood cell and platelet
Nausea and vomiting.
Menstrual changes, early menopause, and decreased sperm
Blood in the urine because of irritation of the bladder. Be sure
to drink at least 8 full glasses of fluid a day if you are being treated with
See Drug Reference for a full list of side effects. (Drug
Reference is not available in all systems.)
affect your ability to have children. You may not be able to become pregnant or
father a child after taking cyclophosphamide. Discuss fertility with your
doctor before starting treatment with this drug.
can cause birth defects. Do not use this medicine if you are pregnant or wish
to become pregnant or father a child while you are taking it.
Women who take this medicine may experience menopausal symptoms,
including hot flashes and vaginal dryness.
How this information was developed to help you make better health decisions.