Health Information

Antidepressant Medicines Used to Treat OCD

What To Think About

Never suddenly stop taking antidepressants. The use of any antidepressant should be tapered off slowly and only under the supervision of a doctor. Abruptly stopping antidepressant medicine can cause negative side effects or a relapse into a depressive episode or anxiety disorder.

If other mental health problems (such as depression) are present along with OCD, other medicines (such as a mood stabilizer or an antianxiety or antipsychotic medicine) also may be needed to effectively treat the combined disorders.

SSRIs can be safer than tricyclic or tetracyclic antidepressants, because they don't cause death if taken in large quantities (overdose). SSRIs usually are well tolerated and effective. SSRIs also may be safer for older adults, because the side effects are more tolerable.

People with liver disease usually need lower doses of SSRIs.

Studies have found that daily use of SSRIs may increase the risk of bone fracture in adults over age 50. Talk to your doctor about this risk before taking an SSRI.

SSRIs make bleeding more likely in the upper gastrointestinal tract (stomach and esophagus). Taking SSRIs with NSAIDs (such as Aleve or Advil) makes bleeding even more likely. Taking medicines that control acid in the stomach may help.^{Reference 1}

SSRIs are also used to treat depression. SSRIs alone aren't commonly used if you have episodes of Reference mania Opens New Window, such as in Reference bipolar disorder Opens New Window.

Sexual dysfunction can be a significant problem for some people while taking an SSRI. A medicine such as sildenafil (Viagra) may help both men and women who have sexual problems caused by SSRIs.^{Reference 2,} ^{Reference 3}

Taking medicine

Medicine is one of the many tools your doctor has to treat a health problem. Taking medicine as your doctor suggests will improve your health and may prevent future problems. If you don't take your medicines properly, you may be putting your health (and perhaps your life) at risk.

There are many reasons why people have trouble taking their medicine. But in most cases, there is something you can do. For suggestions on how to work around common problems, see the topic Reference Taking Medicines as Prescribed.

Advice for women

Women who take an SSRI during pregnancy have a slightly higher chance of having a baby with birth defects. If you are pregnant, you and your doctor must weigh the risks of taking an SSRI against the risks of not treating your anxiety disorder.

Checkups

Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.

By:	Reference Healthwise Staff	Last Revised: June 5, 2012
Medical Review:	Reference Patrice Burgess, MD - Family Medicine Reference Lisa S. Weinstock, MD - Psychiatry