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    Oral Diabetes Medicines That Can Cause Low Blood Sugar

    Oral Diabetes Medicines That Can Cause Low Blood Sugar

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    Topic Overview

    Sulfonylureas can cause low blood sugar. They help the pancreas release insulin.

    • Chlorpropamide (Diabinese)
    • Glimepiride (Amaryl)
    • Glipizide (Glucotrol)
    • Glyburide (DiaBeta, Glynase, Micronase)
    • Tolbutamide
    • Tolazamide

    Meglitinides help the pancreas release insulin. They may cause low blood sugar.

    • Nateglinide (Starlix)
    • Repaglinide (Prandin)

    Alpha-glucosidase inhibitors lower your blood sugar. They do this by slowing the digestion of carbohydrates.

    • Acarbose (Precose)
    • Miglitol (Glyset)

    You are less likely to get low blood sugar if you take:

    • DPP-4 inhibitors. These include sitagliptin (Januvia) and saxagliptin (Onglyza).
    • Metformin. One brand name is Glucophage.
    • Sodium glucose co-transporter 2 inhibitors. These include canagliflozin (Invokana), dapagliflozin (Farxiga), and empagliflozin (Jardiance).
    • Thiazolidinediones. These include pioglitazone (Actos) and rosiglitazone (Avandia).

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    ByHealthwise Staff
    Primary Medical Reviewer E. Gregory Thompson, MD - Internal Medicine
    Kathleen Romito, MD - Family Medicine
    Adam Husney, MD - Family Medicine
    Specialist Medical Reviewer Theresa O'Young, PharmD - Clinical Pharmacy
    David C.W. Lau, MD, PhD, FRCPC - Endocrinology

    Current as ofAugust 3, 2016

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