Common brand names:Copegus, Rebetol, Ribasphere, RibaPak, Ribatab
Summary of Interactions with Vitamins, Herbs, & Foods
Replenish Depleted Nutrients
Reduce Side Effects
Anemia is one of the side effects of ribavirin therapy. In a preliminary trial, supplementing with EPA partially prevented the decline in hemoglobin levels in patients with hepatitis C who were being treated with the combination of ribavirin and pegylated interferon alpha-2b.1
In a randomized trial, patients with chronic hepatitis C who were being treated with Peg-interferon-alpha 2b and ribavirin were randomly assigned to receive L-carnitine (2 grams twice a day) or no L-carnitine (control group). Compared with the control group, fewer patients in the L-carnitine group had to reduce the medication dosage or discontinue treatment because of side effects such as anemia or a decline in the white blood cell count.2
Potential Negative Interaction
1. Suzuki M, Inage E, Minowa K, et al. Prophylaxis for ribavirin-related anemia using eicosapentaenoic acid in chronic hepatitis C patients. Pediatr Int 2012;54:528-31.
2. Malaguarnera M, Vacante M, Giordano M, et al. L-carnitine supplementation improves hematological pattern in patients affected by HCV treated with Peg interferon-alpha 2b plus ribavirin. World J Gastroenterol 2011;17:4414-20.
Last Review: 05-01-2013
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