These abnormal triglyceride and HDL levels can raise your risk for the problems that affect the large blood vessels. When blood vessels that supply the brain and heart are affected, a stroke or heart attack may occur.
When the large blood vessels in the legs are affected, problems with blood circulation to the legs and feet may occur. This can cause changes in skin color, decreased sensation, and leg cramps. This type of problem is called peripheral arterial disease (PAD).
Cholesterol problems may also develop if you have diabetic nephropathy, even in the early stages when your kidney is losing small amounts of protein.
Heart-healthy lifestyle changes along with medicine can lower your cholesterol and your risk for heart attack and stroke. A heart-healthy lifestyle includes eating healthy foods, being active, staying at a healthy weight, and not smoking.