Main content

    Health Information

    Cycloserine

    Topic Contents

    Cycloserine

    Drug Information

    Cycloserine is a broad-spectrum antibiotic used to treat tuberculosis. It is used rarely for treating noninfectious diseases.

    Common brand names:

    Seromycin

    Summary of Interactions with Vitamins, Herbs, & Foods

    Types of interactions: Beneficial Adverse Check

    Replenish Depleted Nutrients

    • Vitamin K

      Many antibiotics taken by mouth, including cycloserine, may kill friendly bacteria in the large intestine that produce vitamin K.1 With short-term (a few weeks or less) antibiotic use, the actions on vitamin K are usually mild and cause no problems. After antibiotic therapy is completed, vitamin K activity returns to normal.

    • Calcium

      Cycloserine may interfere with calcium and magnesium absorption.2 The clinical significance of these interactions is unclear.

      Cycloserine may interfere with the absorption and/or activity of folic acid, vitamin B6, and vitamin B12.3 , 4 The clinical importance of this interaction is unclear.

      The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
    • Folic Acid

      Cycloserine may interfere with calcium and magnesium absorption.5 The clinical significance of these interactions is unclear.

      Cycloserine may interfere with the absorption and/or activity of folic acid, vitamin B6, and vitamin B12.6 , 7 The clinical importance of this interaction is unclear.

      The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
    • Magnesium

      Cycloserine may interfere with calcium and magnesium absorption.8 The clinical significance of these interactions is unclear.

      Cycloserine may interfere with the absorption and/or activity of folic acid, vitamin B6, and vitamin B12.9 , 10 The clinical importance of this interaction is unclear.

      The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
    • Vitamin B12

      Cycloserine may interfere with calcium and magnesium absorption.11 The clinical significance of these interactions is unclear.

      Cycloserine may interfere with the absorption and/or activity of folic acid, vitamin B6, and vitamin B12.12 , 13 The clinical importance of this interaction is unclear.

      The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
    • Vitamin B6

      Cycloserine may interfere with calcium and magnesium absorption.14 The clinical significance of these interactions is unclear.

      Cycloserine may interfere with the absorption and/or activity of folic acid, vitamin B6, and vitamin B12.15 , 16 The clinical importance of this interaction is unclear.

      The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.

    Reduce Side Effects

    • none

    Support Medicine

    • none

    Reduces Effectiveness

    • none

    Potential Negative Interaction

    • none

    Explanation Required 

    • none

    The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers' package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

    References

    1. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

    2. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

    3. Roe D, Campbell T, eds. Drugs and Nutrients: The Interactive Effects. New York: Marcel Decker, 1984, 288-9, 505-23.

    4. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

    5. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

    6. Roe D, Campbell T, eds. Drugs and Nutrients: The Interactive Effects. New York: Marcel Decker, 1984, 288-9, 505-23.

    7. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

    8. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

    9. Roe D, Campbell T, eds. Drugs and Nutrients: The Interactive Effects. New York: Marcel Decker, 1984, 288-9, 505-23.

    10. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

    11. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

    12. Roe D, Campbell T, eds. Drugs and Nutrients: The Interactive Effects. New York: Marcel Decker, 1984, 288-9, 505-23.

    13. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

    14. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

    15. Roe D, Campbell T, eds. Drugs and Nutrients: The Interactive Effects. New York: Marcel Decker, 1984, 288-9, 505-23.

    16. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 86.

    This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

    Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.