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    Hydralazine

    Topic Contents

    Hydralazine

    Drug Information

    Hydralazine is a drug used to lower blood pressure in people with hypertension . Hydralazine relaxes the muscles that control the diameter of blood vessels. This relaxation allows the blood vessels to dilate (open wider), lowering blood pressure.

    Common brand names:

    Apresoline

    Summary of Interactions with Vitamins, Herbs, & Foods

    Types of interactions: Beneficial Adverse Check

    Replenish Depleted Nutrients

    • Vitamin B6

      Vitamin B6 can bind to hydralazine to form a complex that is excreted in the urine, increasing vitamin B6 loss.1 This may lead to vitamin B6 deficiency.2 People taking hydralazine should consult with their doctor to discuss the possibility of vitamin B6 supplementation.

    Reduce Side Effects

    • none

    Support Medicine

    • none

    Reduces Effectiveness

    • none

    Potential Negative Interaction

    • none

    Explanation Required 

    • none

    The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers' package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

    References

    1. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 131-2.

    2. Raskin NH, Rishman RA. Pyridoxine-deficiency neuropathy due to hydralazine. N Engl J Med 1965;273:1182-5.

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