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    Effects of Diethylstilbestrol (DES) Exposure

    Effects of Diethylstilbestrol (DES) Exposure

    Topic Overview

    Between 1948 and 1971, millions of women took a drug called diethylstilbestrol (DES) to prevent miscarriage.

    Daughters born to women who took DES while pregnant have a slightly higher risk of developing:

    • Abnormal cervical cells that cause an abnormal Pap test result.
    • Cancer of the vagina.
    • Structural problems in the reproductive organs (such as a T-shaped uterus), which can cause infertility.


    By Healthwise Staff
    Sarah Marshall, MD - Family Medicine
    Kirtly Jones, MD - Obstetrics and Gynecology
    Last Revised December 12, 2012

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