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    Medicines, Osteoporosis, and Fractures

    Medicines, Osteoporosis, and Fractures

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    Topic Overview

    Many medicines seem to be related to bone fractures or to bone thinning ( osteoporosis ) that can lead to fractures. These medicines include:

    • Corticosteroid medicines . These are used to treat conditions such as asthma and chronic obstructive pulmonary disease (COPD). If you use them for 6 months or longer, they can lead to steroid-induced osteoporosis.
    • Thyroid replacement medicine, if the dose is more than the body needs. This should be monitored by checking the level of thyroid-stimulating hormone (TSH) at least every year.
    • Antiseizure medicines. Examples are carbamazepine and phenytoin.
    • Medicines used to treat endometriosis . They include leuprolide (Lupron) and nafarelin (Synarel).
    • Aromatase inhibitors. These are used to treat breast cancer .
    • Hormone therapy to treat prostate cancer .
    • Some antidepressant medicines called selective serotonin reuptake inhibitors (SSRIs). SSRIs are used to treat many conditions, including depression , fibromyalgia , and premenstrual syndrome .
    • Heparin, if used for a long time. Heparin is a blood thinner.
    • Depo-Provera, if used for a long time. It's a birth control medicine given in a shot.
    • Antacids that contain aluminum, if they are overused. These kinds of antacids remove calcium from your body.
    • Some diabetes medicines. Examples are pioglitazone (Actos) and rosiglitazone (Avandia).

    Related Information


    ByHealthwise Staff
    Primary Medical Reviewer Kathleen Romito, MD - Family Medicine
    Specialist Medical Reviewer Carla J. Herman, MD, MPH - Geriatric Medicine

    Current as ofAugust 4, 2016

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