---
title: "Over-the-Counter Progesterone Cream | Sutter Health"
description: "Is it safe for me to use Pro-G-Yam progesterone cream for hot flashes? I have a family history of breast cancer. Is progesterone the same as estrogen?"
url: "/ask-an-expert/answers/over-the-counter-progesterone-cream-1051061263"
---

1.  Home /
2.  Over-the-Counter Progesterone Cream

# Over-the-Counter Progesterone Cream

* * *

Medically reviewed by

-   Toni J Brayer, M.D.

## Question

Is it safe for me to use Pro-G-Yam progesterone cream for hot flashes? I have a family history of breast cancer. Is progesterone the same as estrogen?

## Answer

There are hundreds of different brands and formulations of progesterone cream. It is considered a "nutraceutical" and is not controlled or regulated by the FDA. You can purchase progesterone creams through the internet or drugstores.

Most of these formulations say they are made from wild yams or soybeans, which contain natural progesterone. Generally these creams are considered safe, however no studies have been done regarding their effectiveness for treating hot flashes or other symptoms of menopause. Progesterone is a female hormone, as is estrogen, and both decline naturally with aging.

## Explore related topics

Women's healthBreast HealthBreast CancerMenopause

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