Jump to content

  • Set Your Location
  • Sign in or Enroll
Set Your LocationMemorial Hospital Los Banos
  • Sign in or Enroll
    • Open I want to choose my medical group or hospital
    • Clear my location
Change Location
Sutter Health
  • Video Visits
  • Find Doctors
  • Find Locations
  • Treatments & Services
    • Video Visits
    • Find Doctors
    • Find Locations
    • Treatments & Services
    • COVID-19 Resources
    • Pay a Bill
    • Symptom Checker
    • Get Care Today
    • Health & Wellness
    • Classes & Events
    • Research & Clinical Trials
    • For Patients
    • About Sutter Health
    • Giving
    • Volunteering
    • Careers
    • News
    • For Medical Professionals
    • Other Business Services
Close Search
  • Home
  • Memorial Hospital Los Banos
  • Research
  • Obesity
Content

Short-term weight trajectories and long-term weight outcomes from a lifestyle intervention in real-world clinical practice.

Description

Romanelli RJ, Sudat S, Huang Q, Ma J, Venditti EM, Greenwood DA, Pressman AR, Azar KMJ., Transl Behav Med. pii: ibz118. doi: 10.1093/tbm/ibz118. [Epub ahead of print], 2019 Aug 01

Investigators

Kristen Azar, R.N., BSN, MSN/MPH, Investigator, Sylvia Sudat, PhD

Abstract

Centers for Disease Control and Prevention aligned lifestyle change programs are effective in promoting weight loss among those with elevated cardiometabolic risk; yet, variability in weight outcomes among participants is high. Little is known about heterogeneity of short-term weight changes among participants in real-world clinical practice.

We sought to identify short-term weight trajectory clusters among lifestyle change program participants in real-world clinical practice and to examine the relationship between cluster membership and long-term weight outcomes.

We identified participants from the electronic health records (2010-2017) with weight measured ≤30 days prior to program initiation (baseline) and in four intervals (3-week segments) in the 12 weeks after baseline. Clustering analysis was performed to identify distinct trajectories in percent weight change over 12 weeks. Cluster-specific differences in weight change at 12 and 52 weeks were assessed.

Among 1,148 participants, across 18 clinic sites, three clusters were identified: minimal-to-no weight loss (MWL), delayed-minimal weight loss (DWL), and steady-moderate weight loss (SWL), corresponding to mean weight changes of 0.4%, -2.3%, and -4.8% at 12 weeks follow-up, respectively. Mean weight changes were 0.4%, -1.8%, and -5.1% for MWL, DWL, and SWL clusters, respectively, at 52 weeks follow-up, which correlated in direction and magnitude with short-term weight changes.

Clustering analysis reveals heterogeneous, short-term weight trajectories among lifestyle change program participants in real-world clinical practice. Given the relationship between the magnitudes of short- and long-term weight change, individual participant weight trajectories may be useful in identifying potential non-responders in need of adjunctive or alternative therapy.

Pubmed Abstract

Pubmed AbstractOpens New Window

Associated Topics

  • Diabetes, Insulin Resistance and Metabolic Syndrome
  • Medical Informatics
  • Obesity

Related Publications

Perioperative complications stratified by body mass index for the direct anterior approach to total hip arthroplasty.

Hartford JM, Graw BP, Frosch DL.
J Arthroplasty. pii: S0883-5403(20)30348-X. doi: 10.1016/j.arth.2020.04.018. [Epub ahead of print]
2020 Apr 11

Variability in engagement and progress in efficacious integrated collaborative care for primary care patients with obesity and depression: within-treatment analysis in the RAINBOW trial.

Lv N, Xiao L, Majd M, Lavori PW, Smyth JM, Rosas LG, Venditti EM, Snowden MB, Lewis MA, Ward E, Lesser L, Williams LM, Azar KMJ, Ma J.
PLoS One. 15(4):e0231743. doi: 10.1371/journal.pone.0231743. eCollection 2020.
2020 Apr 21

Barriers and facilitators to real-world implementation of the Diabetes Prevention Program in large healthcare systems: lifestyle coach perspectives.

Halley MC, Petersen J, Nasrallah C, Szwerinski N, Romanelli R, Azar KMJ.
J Gen Intern Med. doi: 10.1007/s11606-020-05744-y. [Epub ahead of print]
2020 Apr 06

Differing views regarding diet and physical activity: adolescents versus parents' perspectives.

Azar KMJ, Halley M, Lv N, Wulfovich S, Gillespie K, Liang L, Goldman Rosas L.
BMC Pediatr. 20(1):137. doi: 10.1186/s12887-020-02038-4.
2020 Mar 27

Effect of an intervention for obesity and depression on patient-centered outcomes: an RCT.

Rosas LG, Azar KMJ, Lv N, Xiao L, Goldhaber-Fiebert JD, Snowden MB, Venditti EM, Lewis MM, Goldstein-Piekarski AN, Ma J.
Am J Prev Med. pii: S0749-3797(19)30512-4. doi: 10.1016/j.amepre.2019.11.005. [Epub ahead of print]
2020 Feb 14
The Sutter Health Network of Care
Expertise to fit your needs
Primary Care

Check-ups, screenings and sick visits for adults and children.

Specialty Care

Expertise and advanced technologies in all areas of medicine.

Emergency Care

For serious accidents, injuries and conditions that require immediate medical care.

Urgent Care

After-hours, weekend and holiday services.

Walk-In Care

Convenient walk-in care clinics for your non-urgent health needs.

  • Contact Us
  • Find Doctors
  • Find Locations
  • Request Medical Records
  • Make a Gift
Sign in to My Health Online

Billing and Insurance

  • Pay a Bill
  • Accepted Health Plans
  • Estimate Costs
  • Medicare Advantage

About Sutter

  • About Our Network
  • Community Benefit
  • Annual Report
  • News

Our Team

  • For Employees
  • For Medical Professionals
  • For Vendors
  • For Volunteers

Careers

  • Jobs at Sutter
  • Physician Jobs
  • Graduate Medical Education

Copyright © 2023 Sutter Health. All rights reserved. Sutter Health is a registered trademark of Sutter Health ®, Reg. U.S. Patent & Trademark office.

  • ADA Accessibility
  • Privacy
  • Do Not Sell My Personal Information
  • LinkedIn Opens new window
  • YouTube Opens new window
  • Facebook Opens new window
  • Twitter Opens new window
  • Instagram Opens new window
  • Glassdoor Opens new window

Cookie Policy

We use cookies to give you the best possible user experience. By continuing to use the site, you agree to the use of cookies. Privacy Policy Cookie Preferences

Privacy Policy Cookie Preferences