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Measurement of Quality of Life and Perceived Disease Impact on Quality of Life in Asthma

Description

Existing disease-specific quality of life (QoL) scales do not directly assess QoL or the perceived impact of the disease on QoL. The purpose of this study is to evaluate the properties (reliability, concurrent and longitudinal validity, and responsiveness to change in asthma status) of a new measure of the patient-perceived negative effects of asthma in adults, the Asthma Impact on Quality of Life Scale (A-IQOLS), and to compare its properties with those of a measure of current QoL, the Flanagan Quality of Life Scale (QOLS). The hypothesis is that the approach represented by the A-IQOLS will prove superior to that of the QOLS as an outcome measure for clinical research purposes. This research can fill a significant gap in the currently available tools, with consequent benefit to clinical research and measurement of patient-centered outcomes in other disease areas.

PI is Sandra Wilson, PhD. PAMF Co-Investigators: Michael Mulligan; MD, Alan Chausow, MD; Estela Ayala, MD. Outside Co-Investigators:  Robert Wise, MD, Johns Hopkins University Schools of Medicine and Public Health; Mario Castro, MD, Washington University School of Medicine. 

Principal Investigator

Sandra Wilson, Ph.D.

Funder

National Heart, Lung and Blood Institute/National Institutes of Health

Start Date

April 01, 2014

End Date

March 31, 2017

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