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A Safety and Efficacy Study of Ruxolitinib Cream Combined With Narrow-Band Ultraviolet B Phototherapy in Participants With Vitiligo

Study Information

Status: Active, Recruiting

Study Details

View study details on clinicaltrials.gov.

Locations

Palo Alto/Santa Cruz

Clinical Trial FAQs

Information for patients and study volunteers, including frequently asked questions.

Contact Us to Enroll

Description

An open-label study for patients with vitilgo to assess how ruxolitinib cream works in combination with phototherapy.  Eligible participants will receive treatment free of charge while participating.  Study participation lasts about 56 weeks.

Key Inclusion Criteria:

  1. Adolescents age 12 to 17, and adults
  2. A clinical diagnosis of nonsegmental vitiligo with depigmented area including all of the following:
  •    ≥ 0.5 F-VASI on the face
  •    ≥ 3.0 T-VASI (body areas not including the face)
  •    Total body vitiligo area (facial and nonfacial) not exceeding 10% BSA.

    3. Agree to discontinue all agents used to treat vitiligo from screening through the              final safety follow-up visit. Over-the-counter preparations deemed acceptable by            the investigator and camouflage makeups are permitted.

Principal Investigator

Amit Pandya, Dermatologist

Funder

Incyte Corporation

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