--- title: "ALS Healey Platform Trial Master Protocol | Sutter Health" description: "HEALEY ALS Platform Trial" url: "https://www.sutterhealth.org/research/clinical-trials/als-healey-platform-trial-master-protocol-2057369170" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Clinical trials](https://www.sutterhealth.org/research/clinical-trials) / 4. ALS Healey Platform Trial Master Protocol # ALS Healey Platform Trial Master Protocol **Status:** Closed to Enrollment #### Study details View study details on [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04297683). #### Locations - San Francisco #### Clinical trial FAQs Information for patients and study volunteers, including [frequently asked questions](https://www.sutterhealth.org/research/faqs). ****TEMPORARILY CLOSED TO ENROLLMENT**** The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS. This trial is designed as a perpetual platform trial. This means that there is a single Master Protocol dictating the conduct of the trial. The following regimens are active in the trial: Regimen I - NUZ-001 - Closed to enrollment New regimens will be continuously added as new investigational products become available. The HEALEY ALS Platform Trial will enroll additional participants as each new regimen is available. - Drug: Zilucoplan - Drug: Verdiperstat - Drug: CNM-Au8 - Drug: Pridopidine - Drug: SLS-005 Trehalose - Drug: ABBV-CLS-7262 - Drug: DNL343 ![Jonathan S Katz, M.D.](https://dyn.mktgcdn.com/p/e5XrnYB0_0NPm8BW1zudPpb9L7b73YitfpxL6zIxknY/fit=crop,gravity=auto,dpr=2,width=188,height=250,quality=100) Jonathan S Katz, M.D. Principal investigator [View profile](https://www.sutterhealth.org/research/investigators/jonathan-s-katz-md-1049681078) ## Sub-Investigators [Liberty Jenkins, M.D., MRCP, MA](https://www.sutterhealth.org/research/investigators/liberty-jenkins-md-mrcp-ma-1049681060) , [Nancy G Palmer, N.P.](https://www.sutterhealth.org/research/investigators/nancy-g-palmer-np-2044041768) ## Related clinical trials [View all clinical trials](https://www.sutterhealth.org/research-search-results?verticalKey=clinical_trial) - Clinical trial ### [ALS SPG302 Expanded Access Protocol](https://www.sutterhealth.org/research/clinical-trials/als-spg302-expanded-access-protocol-2036968358) Intermediate-size Patient Population Expanded Access Protocol for SPG302 in Adult Patients With Amyotrophic Lateral Sclerosis (ALS) **Status:** Open to Enrollment - Clinical trial ### [Amyotrophic Lateral Sclerosis (ALS) C302-CLN-2301](https://www.sutterhealth.org/research/clinical-trials/amyotrophic-lateral-sclerosis-als-c302-cln-2301-2044044761) Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multi-Center, 24-Week Study With Additional 24-Week Blinded Active Extension to Evaluate the Safety and Efficacy of COYA 302 for the Treatment of Amyotrophic Lateral Sclerosis (ALS) **Status:** Open to Enrollment - Clinical trial ### [Amyotrophic Lateral Sclerosis (ALS) PL101-ALS301 PREVAILS](https://www.sutterhealth.org/research/clinical-trials/amyotrophic-lateral-sclerosis-als-pl101-als301-prevails-2064309735) A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Pridopidine in Participants With Amyotrophic Lateral Sclerosis **Status:** Open to Enrollment - Clinical trial ### [Amyotrophic Lateral Sclerosis (ALS) UNITE-ALS USNO.24.002](https://www.sutterhealth.org/research/clinical-trials/amyotrophic-lateral-sclerosis-als-unite-als-usno24002-2064309948) A Phase 2b, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Usnoflast Administered to Adult Subjects With ALS UNITE-ALS USNO.24.002 **Status:** Open to Enrollment - Clinical trial ### [Acute Ischemic Stroke PICASSO](https://www.sutterhealth.org/research/clinical-trials/acute-ischemic-stroke-picasso-1094825919) Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial **Status:** Open to Enrollment [View all clinical trials](https://www.sutterhealth.org/research-search-results?verticalKey=clinical_trial) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]} ``` ```json {"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/clinical-trials/als-healey-platform-trial-master-protocol-2057369170#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Clinical trials","item":"https://www.sutterhealth.org/research/clinical-trials"},{"@type":"ListItem","position":4,"name":"ALS Healey Platform Trial Master Protocol"}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalWebPage","@id":"https://www.sutterhealth.org/research/clinical-trials/als-healey-platform-trial-master-protocol-2057369170#medicalwebpage","name":"ALS Healey Platform Trial Master Protocol","description":"HEALEY ALS Platform Trial","url":"https://www.sutterhealth.org/research/clinical-trials/als-healey-platform-trial-master-protocol-2057369170","inLanguage":"en-US","dateModified":"2026-08-24","publisher":{"@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org"},"medicalAudience":{"@type":"MedicalAudience","audienceType":"Patient"},"mainEntity":{"@id":"https://www.sutterhealth.org/research/clinical-trials/als-healey-platform-trial-master-protocol-2057369170#medicaltrial"},"breadcrumb":{"@id":"https://www.sutterhealth.org/research/clinical-trials/als-healey-platform-trial-master-protocol-2057369170#breadcrumblist"},"mentions":[{"@type":"Person","name":"Jonathan S Katz, M.D.","url":"https://www.sutterhealth.org/research/investigators/jonathan-s-katz-md-1049681078","jobTitle":"Principal Investigator","affiliation":{"@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org"}}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalTrial","@id":"https://www.sutterhealth.org/research/clinical-trials/als-healey-platform-trial-master-protocol-2057369170#medicaltrial","name":"ALS Healey Platform Trial Master Protocol","alternateName":"HEALEY ALS Platform Trial","url":"https://www.sutterhealth.org/research/clinical-trials/als-healey-platform-trial-master-protocol-2057369170","description":"TEMPORARILY CLOSED TO ENROLLMENT The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS. 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