--- title: "Chondral Defect Bone Marrow Stimulation MASCOT | Sutter Health" description: "A Prospective, Open-label, Randomized, Concurrent Active-controlled, Longitudinal, Multicenter, Phase 3 Clinical Study of the Safety and Efficacy of MACI in Patients With Symptomatic Chondral or Osteochondral Lesions of the Talus (MASCOT)" url: "https://www.sutterhealth.org/research/clinical-trials/chondral-defect-bone-marrow-stimulation-mascot-2096506282" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Clinical trials](https://www.sutterhealth.org/research/clinical-trials) / 4. Chondral Defect Bone Marrow Stimulation MASCOT # Chondral Defect Bone Marrow Stimulation MASCOT **Status:** Open to Enrollment [Email us to enroll](https://www.sutterhealth.org/research/clinical-trials/chondral-defect-bone-marrow-stimulation-mascot-2096506282#enroll) #### Study details View study details on [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06915233). #### Locations - Castro Valley #### Clinical trial FAQs Information for patients and study volunteers, including [frequently asked questions](https://www.sutterhealth.org/research/faqs). A Prospective, Open-label, Randomized, Concurrent Active-controlled, Longitudinal, Multicenter, Phase 3 Clinical Study of the Safety and Efficacy of MACI in Patients With Symptomatic Chondral or Osteochondral Lesions of the Talus (MASCOT) ![Deryk G Jones, M.D.](https://dyn.mktgcdn.com/p/sCydOL45FCX1M2TxZKHpV3mtsE3D1Bw26WbbeML5_rQ/fit=crop,gravity=auto,dpr=2,width=188,height=250,quality=100) Deryk G Jones, M.D. Principal investigator [View profile](https://www.sutterhealth.org/research/investigators/deryk-g-jones-md-2096506476) ## Email us to enroll - [Email Castro Valley](mailto:ClinicalResearch%40sutterhealth.org?subject=More%20information%20on%20Chondral%20Defect%20Bone%20Marrow%20Stimulation%20MASCOT%20in%20Castro%20Valley&body=Please%20be%20aware%20that%20if%20you%20reply%20with%20unencrypted%20email%2C%20this%20increases%20the%20risk%20that%20information%20could%20be%20read%20by%20an%20unauthorized%20third%20party.%20Please%20do%20not%20include%20any%20Protected%20Health%20Information%20in%20your%20email%20response.) ## Related clinical trials [View all clinical trials](https://www.sutterhealth.org/research-search-results?verticalKey=clinical_trial) - Clinical trial ### [Knee Cartilage Defects CARTISTEM® + Debridement MPA-CARTISTEM-2023-01](https://www.sutterhealth.org/research/clinical-trials/knee-cartilage-defects-cartistem-debridement-mpa-cartistem-2023-01-2102453852) Randomized, Prospective, Double Blind, Multi-Center, Phase 3 Pivotal Clinical Trial to Compare Efficacy and Safety of CARTISTEM® and Surgical Comparator in Subjects With Knee Cartilage Lesions and Osteoarthritis **Status:** Coming Soon [View all clinical trials](https://www.sutterhealth.org/research-search-results?verticalKey=clinical_trial) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]} ``` ```json {"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/clinical-trials/chondral-defect-bone-marrow-stimulation-mascot-2096506282#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Clinical trials","item":"https://www.sutterhealth.org/research/clinical-trials"},{"@type":"ListItem","position":4,"name":"Chondral Defect Bone Marrow Stimulation MASCOT"}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalWebPage","@id":"https://www.sutterhealth.org/research/clinical-trials/chondral-defect-bone-marrow-stimulation-mascot-2096506282#medicalwebpage","name":"Chondral Defect Bone Marrow Stimulation MASCOT","description":"A Prospective, Open-label, Randomized, Concurrent Active-controlled, Longitudinal, Multicenter, Phase 3 Clinical Study of the Safety and Efficacy of MACI in Patients With Symptomatic Chondral or Osteochondral Lesions of the Talus (MASCOT)","url":"https://www.sutterhealth.org/research/clinical-trials/chondral-defect-bone-marrow-stimulation-mascot-2096506282","inLanguage":"en-US","dateModified":"2026-10-19","publisher":{"@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org"},"medicalAudience":{"@type":"MedicalAudience","audienceType":"Patient"},"mainEntity":{"@id":"https://www.sutterhealth.org/research/clinical-trials/chondral-defect-bone-marrow-stimulation-mascot-2096506282#medicaltrial"},"breadcrumb":{"@id":"https://www.sutterhealth.org/research/clinical-trials/chondral-defect-bone-marrow-stimulation-mascot-2096506282#breadcrumblist"},"mentions":[{"@type":"Person","name":"Deryk G Jones, M.D.","url":"https://www.sutterhealth.org/research/investigators/deryk-g-jones-md-2096506476","jobTitle":"Principal Investigator","affiliation":{"@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org"}}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalTrial","@id":"https://www.sutterhealth.org/research/clinical-trials/chondral-defect-bone-marrow-stimulation-mascot-2096506282#medicaltrial","name":"Chondral Defect Bone Marrow Stimulation MASCOT","alternateName":"A Prospective, Open-label, Randomized, Concurrent Active-controlled, Longitudinal, Multicenter, Phase 3 Clinical Study of the Safety and Efficacy of MACI in Patients With Symptomatic Chondral or Osteochondral Lesions of the Talus (MASCOT)","url":"https://www.sutterhealth.org/research/clinical-trials/chondral-defect-bone-marrow-stimulation-mascot-2096506282","description":"A Prospective, Open-label, Randomized, Concurrent Active-controlled, Longitudinal, Multicenter, Phase 3 Clinical Study of the Safety and Efficacy of MACI in Patients With Symptomatic Chondral or Osteochondral Lesions of the Talus (MASCOT)","identifier":"NCT06915233","code":{"@type":"MedicalCode","codeValue":"NCT06915233","codingSystem":"ClinicalTrials.gov"},"sameAs":"https://clinicaltrials.gov/study/NCT06915233","status":"https://schema.org/Recruiting","studyLocation":[{"@type":"AdministrativeArea","name":"Castro Valley"}]} ```