---
title: "Hepatitis LCAH3141 RE-AHFIRM | Sutter Health"
description: "RE-AHFIRM (RandomizEd Study of Larsucosterol in Alcohol-associated Hepatitis to Confirm saFety and effIcacy of tReatMent)"
url: "https://www.sutterhealth.org/research/clinical-trials/hepatitis-lcah3141-re-ahfirm-2075020771"
---

1.  [Home](https://www.sutterhealth.org/) /
2.  [Research](https://www.sutterhealth.org/research) /
3.  [Clinical trials](https://www.sutterhealth.org/research/clinical-trials) /
4.  Hepatitis LCAH3141 RE-AHFIRM

# Hepatitis LCAH3141 RE-AHFIRM

**Status:** Open to Enrollment

[Email us to enroll](https://www.sutterhealth.org/research/clinical-trials/hepatitis-lcah3141-re-ahfirm-2075020771#enroll)

#### Study details

View study details on [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07428538).

#### Locations

-   San Francisco

#### Clinical trial FAQs

Information for patients and study volunteers, including [frequently asked questions](https://www.sutterhealth.org/research/faqs).

RE-AHFIRM (RandomizEd Study of Larsucosterol in Alcohol-associated Hepatitis to Confirm saFety and effIcacy of tReatMent)

![R Todd Frederick, M.D.](https://dyn.mktgcdn.com/p/DYa8wdK5N75wVC66dzWg4-1m5SyalXxULZ9bQLcc80o/fit=crop,gravity=auto,dpr=2,width=188,height=250,quality=100)

R Todd Frederick, M.D.

Principal investigator

[View profile](https://www.sutterhealth.org/research/investigators/r-todd-frederick-md-1049681184)

## Sub-Investigator

[Debra W Yen, M.D.](https://www.sutterhealth.org/research/investigators/debra-w-yen-md-2075021818)

## Email us to enroll

-   [Email San Francisco](mailto:ClinicalResearch%40sutterhealth.org?subject=More%20information%20on%20Hepatitis%20LCAH3141%20RE-AHFIRM%20in%20San%20Francisco&body=Please%20be%20aware%20that%20if%20you%20reply%20with%20unencrypted%20email%2C%20this%20increases%20the%20risk%20that%20information%20could%20be%20read%20by%20an%20unauthorized%20third%20party.%20Please%20do%20not%20include%20any%20Protected%20Health%20Information%20in%20your%20email%20response.)

## Related clinical trials

[View all clinical trials](https://www.sutterhealth.org/research-search-results?verticalKey=clinical_trial)

-   Clinical trial
    
    ### [Stress Urinary Incontinence PAS001 ProACT](https://www.sutterhealth.org/research/clinical-trials/stress-urinary-incontinence-pas001-proact-2080051902)
    
    Post Approval Study of the ProACT™ Adjustable Continence Therapy for Men
    
    **Status:** Open to Enrollment
    
-   Clinical trial
    
    ### [Chronic Nausea and Vomiting NAVIGATE](https://www.sutterhealth.org/research/clinical-trials/chronic-nausea-and-vomiting-navigate-2023207930)
    
    A Prospective Randomized Controlled Trial of Chronic Nausea and Vomiting in Patients With Normal Gastric Emptying Using the Enterra® Therapy System
    
    **Status:** Open to Enrollment
    
-   Clinical trial
    
    ### [Gastroparesis EXPEDITE](https://www.sutterhealth.org/research/clinical-trials/gastroparesis-expedite-2007479109)
    
    Examination of Programming with the Enterra® Therapy System (EXPEDITE) in a Double-Blinded, Randomized, Prospective Study in the Treatment of Nausea and Vomiting Symptoms Using Gastric Electrical Stimulation
    
    **Status:** Open to Enrollment
    
-   Clinical trial
    
    ### [Kidney Transplant Patients EFC18554 FREXERA](https://www.sutterhealth.org/research/clinical-trials/kidney-transplant-patients-efc18554-frexera-2090973869)
    
    A Seamless Phase 2/3 Randomized, Open-label Study to Investigate Efficacy and Safety of Frexalimab Versus Tacrolimus in Adult Kidney Transplant Recipients
    
    **Status:** Coming Soon
    
-   Clinical trial
    
    ### [Microvascular Inflammation in Transplanted Kidney TRANSPIRE](https://www.sutterhealth.org/research/clinical-trials/microvascular-inflammation-in-transplanted-kidney-transpire-2048783395)
    
    A Double-Blind, Placebo-Controlled, Multicenter, Randomized Phase 2 Trial Evaluating the Efficacy and Safety of Felzartamab in Recipients of Kidney Transplants With Late Isolated Microvascular Inflammation (MVI)
    
    **Status:** Open to Enrollment
    

[View all clinical trials](https://www.sutterhealth.org/research-search-results?verticalKey=clinical_trial)

```json
{"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]}
```

```json
{"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/clinical-trials/hepatitis-lcah3141-re-ahfirm-2075020771#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Clinical trials","item":"https://www.sutterhealth.org/research/clinical-trials"},{"@type":"ListItem","position":4,"name":"Hepatitis LCAH3141 RE-AHFIRM"}]}
```

```json
{"@context":"https://schema.org","@type":"MedicalWebPage","@id":"https://www.sutterhealth.org/research/clinical-trials/hepatitis-lcah3141-re-ahfirm-2075020771#medicalwebpage","name":"Hepatitis LCAH3141 RE-AHFIRM","description":"RE-AHFIRM (RandomizEd Study of Larsucosterol in Alcohol-associated Hepatitis to Confirm saFety and effIcacy of tReatMent)","url":"https://www.sutterhealth.org/research/clinical-trials/hepatitis-lcah3141-re-ahfirm-2075020771","inLanguage":"en-US","dateModified":"2026-07-22","publisher":{"@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org"},"medicalAudience":{"@type":"MedicalAudience","audienceType":"Patient"},"mainEntity":{"@id":"https://www.sutterhealth.org/research/clinical-trials/hepatitis-lcah3141-re-ahfirm-2075020771#medicaltrial"},"breadcrumb":{"@id":"https://www.sutterhealth.org/research/clinical-trials/hepatitis-lcah3141-re-ahfirm-2075020771#breadcrumblist"},"mentions":[{"@type":"Person","name":"R Todd Frederick, M.D.","url":"https://www.sutterhealth.org/research/investigators/r-todd-frederick-md-1049681184","jobTitle":"Principal Investigator","affiliation":{"@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org"}}]}
```

```json
{"@context":"https://schema.org","@type":"MedicalTrial","@id":"https://www.sutterhealth.org/research/clinical-trials/hepatitis-lcah3141-re-ahfirm-2075020771#medicaltrial","name":"Hepatitis LCAH3141 RE-AHFIRM","alternateName":"RE-AHFIRM (RandomizEd Study of Larsucosterol in Alcohol-associated Hepatitis to Confirm saFety and effIcacy of tReatMent)","url":"https://www.sutterhealth.org/research/clinical-trials/hepatitis-lcah3141-re-ahfirm-2075020771","description":"RE-AHFIRM (RandomizEd Study of Larsucosterol in Alcohol-associated Hepatitis to Confirm saFety and effIcacy of tReatMent)","identifier":"NCT07428538","code":{"@type":"MedicalCode","codeValue":"NCT07428538","codingSystem":"ClinicalTrials.gov"},"sameAs":"https://clinicaltrials.gov/study/NCT07428538","status":"https://schema.org/Recruiting","healthCondition":[{"@type":"MedicalCondition","name":"Hepatitis, Alcohol-Associated"}],"studyLocation":[{"@type":"AdministrativeArea","name":"San Francisco"}]}
```
