--- title: "Knee Cartilage Defects CARTISTEM® + Debridement MPA-CARTISTEM-2023-01 | Sutter Health" description: "Randomized, Prospective, Double Blind, Multi-Center, Phase 3 Pivotal Clinical Trial to Compare Efficacy and Safety of CARTISTEM® and Surgical Comparator in Subjects With Knee Cartilage Lesions and Osteoarthritis" url: "https://www.sutterhealth.org/research/clinical-trials/knee-cartilage-defects-cartistem-debridement-mpa-cartistem-2023-01-2102453852" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Clinical trials](https://www.sutterhealth.org/research/clinical-trials) / 4. Knee Cartilage Defects CARTISTEM® + Debridement MPA-CARTISTEM-2023-01 # Knee Cartilage Defects CARTISTEM® + Debridement MPA-CARTISTEM-2023-01 **Status:** Coming Soon #### Study details View study details on [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07339111). #### Locations - Sacramento #### Clinical trial FAQs Information for patients and study volunteers, including [frequently asked questions](https://www.sutterhealth.org/research/faqs). Randomized, Prospective, Double Blind, Multi-Center, Phase 3 Pivotal Clinical Trial to Compare Efficacy and Safety of CARTISTEM® and Surgical Comparator in Subjects With Knee Cartilage Lesions and Osteoarthritis ![Cassandra A Lee, M.D.](https://dyn.mktgcdn.com/p/qcKYvPgM2keSa8KHFJ9QgYlWnoXVKRI-e0aAFBCtkj8/fit=crop,gravity=auto,dpr=2,width=188,height=250,quality=100) Cassandra A Lee, M.D. Principal investigator [View profile](https://www.sutterhealth.org/research/investigators/cassandra-a-lee-md-2070259628) ## Sub-Investigator [Jonathan D Hughes, M.D., PhD](https://www.sutterhealth.org/research/investigators/jonathan-d-hughes-md-phd-2102453272) ## Related clinical trials [View all clinical trials](https://www.sutterhealth.org/research-search-results?verticalKey=clinical_trial) - Clinical trial ### [Chondral Defect Bone Marrow Stimulation MASCOT](https://www.sutterhealth.org/research/clinical-trials/chondral-defect-bone-marrow-stimulation-mascot-2096506282) A Prospective, Open-label, Randomized, Concurrent Active-controlled, Longitudinal, Multicenter, Phase 3 Clinical Study of the Safety and Efficacy of MACI in Patients With Symptomatic Chondral or Osteochondral Lesions of the Talus (MASCOT) **Status:** Open to Enrollment [View all clinical trials](https://www.sutterhealth.org/research-search-results?verticalKey=clinical_trial) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza 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