--- title: "Metastatic Prostate Cancer PSMAcTION CAAA817A12201 | Sutter Health" description: "PSMAcTION: A Phase II/III, Open-label, International, Multicenter, Randomized Study of AAA817 Versus Standard of Care in the Treatment of Adult Participants With PSMA Positive Metastatic Castration-resistant Prostate Cancer Who Progressed on or After [177Lu]Lu-PSMA Targeted Therapy" url: "https://www.sutterhealth.org/research/clinical-trials/metastatic-prostate-cancer-psmaction-caaa817a12201-2097344168" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Clinical trials](https://www.sutterhealth.org/research/clinical-trials) / 4. Metastatic Prostate Cancer PSMAcTION CAAA817A12201 # Metastatic Prostate Cancer PSMAcTION CAAA817A12201 **Status:** Open to Enrollment [Email us to enroll](https://www.sutterhealth.org/research/clinical-trials/metastatic-prostate-cancer-psmaction-caaa817a12201-2097344168#enroll) #### Study details View study details on [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06780670). #### Locations - Santa Barbara #### Clinical trial FAQs Information for patients and study volunteers, including [frequently asked questions](https://www.sutterhealth.org/research/faqs). PSMAcTION: A Phase II/III, Open-label, International, Multicenter, Randomized Study of AAA817 Versus Standard of Care in the Treatment of Adult Participants With PSMA Positive Metastatic Castration-resistant Prostate Cancer Who Progressed on or After \[177Lu\]Lu-PSMA Targeted Therapy ![Gregg C Newman, M.D.](https://dyn.mktgcdn.com/p/eVDt8GBNHJ0QudFYw0aWoA_xvD35pHM1Hir7WCNnYKk/fit=crop,gravity=auto,dpr=2,width=188,height=250,quality=100) Gregg C Newman, M.D. Principal investigator [View profile](https://www.sutterhealth.org/research/investigators/gregg-c-newman-md-1097247316) ## Email us to enroll - [Email Santa Barbara](mailto:ClinicalResearch%40sutterhealth.org?subject=More%20information%20on%20Metastatic%20Prostate%20Cancer%20PSMAcTION%20CAAA817A12201%20in%20Santa%20Barbara&body=Please%20be%20aware%20that%20if%20you%20reply%20with%20unencrypted%20email%2C%20this%20increases%20the%20risk%20that%20information%20could%20be%20read%20by%20an%20unauthorized%20third%20party.%20Please%20do%20not%20include%20any%20Protected%20Health%20Information%20in%20your%20email%20response.) ## Related clinical trials [View all clinical trials](https://www.sutterhealth.org/research-search-results?verticalKey=clinical_trial) - Clinical trial ### [Metastatic Castration Resistant Prostate Cancer CAAA817B12301 ActFirst](https://www.sutterhealth.org/research/clinical-trials/metastatic-castration-resistant-prostate-cancer-caaa817b12301-actfirst-2045398589) A Phase III, Open-label, Multi-center, Randomized Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive Metastatic Castration Resistant Prostate Cancer **Status:** Open to Enrollment - Clinical trial ### [Metastatic Prostate Cancer BNT325-03](https://www.sutterhealth.org/research/clinical-trials/metastatic-prostate-cancer-bnt325-03-2097344194) A Phase III, Randomized, Open-label Trial of BNT324 Versus Docetaxel With Prednisone/Prednisolone in Metastatic Castration-resistant Prostate Cancer **Status:** Open to Enrollment - Clinical trial ### [Prostate Cancer Recurrence After Prostatectomy Barrigel®](https://www.sutterhealth.org/research/clinical-trials/prostate-cancer-recurrence-after-prostatectomy-barrigel-2055389985) Randomized Trial of Barrigel® to Increase Distance Between the Rectum and Prostate Bed to Decrease Rectal Dose in Patients Receiving Moderately Hypofractionated Radiation Therapy Who Have Had Recurrence of Prostate Cancer After Prostatectomy **Status:** Open to Enrollment - Clinical trial ### [Advanced Cervical Cancer NRG GY037](https://www.sutterhealth.org/research/clinical-trials/advanced-cervical-cancer-nrg-gy037-2097344123) A Phase III Study of Induction Pembrolizumab and Chemotherapy Followed by Chemoradiation and Pembrolizumab vs Chemoradiation and Pembrolizumab Both Followed by Pembrolizumab for High Risk Locally Advanced Cervical Cancer **Status:** Open to Enrollment - Clinical trial ### [Advanced Staged Cancer Targeted Therapy ASCO TAPUR](https://www.sutterhealth.org/research/clinical-trials/targeted-agent-and-profiling-utilization-registry-tapur-st-1049141787) Targeted Agent and Profiling Utilization Registry (TAPUR) Study **Status:** Open to Enrollment [View all clinical trials](https://www.sutterhealth.org/research-search-results?verticalKey=clinical_trial) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter 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