--- title: "Untreated, Unresectable or Metastatic Colorectal Cancer CA266-0003 ROSETTA | Sutter Health" description: "ROSETTA CRC-203: A Blinded, Randomized Phase 2/3 Study of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer" url: "https://www.sutterhealth.org/research/clinical-trials/untreated-unresectable-or-metastatic-colorectal-cancer-ca266-0003-rosetta-2098340577" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Clinical trials](https://www.sutterhealth.org/research/clinical-trials) / 4. Untreated, Unresectable or Metastatic Colorectal Cancer CA266-0003 ROSETTA # Untreated, Unresectable or Metastatic Colorectal Cancer CA266-0003 ROSETTA **Status:** Open to Enrollment [Email us to enroll](https://www.sutterhealth.org/research/clinical-trials/untreated-unresectable-or-metastatic-colorectal-cancer-ca266-0003-rosetta-2098340577#enroll) #### Study details View study details on [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07221357). #### Locations - San Francisco #### Clinical trial FAQs Information for patients and study volunteers, including [frequently asked questions](https://www.sutterhealth.org/research/faqs). ROSETTA CRC-203: A Blinded, Randomized Phase 2/3 Study of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer ![Ari D Baron, M.D.](https://dyn.mktgcdn.com/p/6yRtgxCIIRXiFOeBSBsWHHTovMS-k88mwc-hVtYQXNU/fit=crop,gravity=auto,dpr=2,width=188,height=250,quality=100) Ari D Baron, M.D. Principal investigator [View profile](https://www.sutterhealth.org/research/investigators/ari-d-baron-md-1049681174) ## Sub-Investigator [Gauri D Kelekar, M.D.](https://www.sutterhealth.org/research/investigators/gauri-d-kelekar-md-1049681156) ## Email us to enroll - [Email San Francisco](mailto:ClinicalResearch%40sutterhealth.org?subject=More%20information%20on%20Untreated%2C%20Unresectable%20or%20Metastatic%20Colorectal%20Cancer%20CA266-0003%20ROSETTA%20in%20San%20Francisco&body=Please%20be%20aware%20that%20if%20you%20reply%20with%20unencrypted%20email%2C%20this%20increases%20the%20risk%20that%20information%20could%20be%20read%20by%20an%20unauthorized%20third%20party.%20Please%20do%20not%20include%20any%20Protected%20Health%20Information%20in%20your%20email%20response.) ## Related clinical trials [View all clinical trials](https://www.sutterhealth.org/research-search-results?verticalKey=clinical_trial) - Clinical trial ### [Adjuvant Colon Cancer GI008](https://www.sutterhealth.org/research/clinical-trials/adjuvant-colon-cancer-gi008-2022194840) Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease **Status:** Open to Enrollment - Clinical trial ### [Adjuvant Colorectal Cancer Stage II/III ctDNA+ BNT122-01](https://www.sutterhealth.org/research/clinical-trials/adjuvant-colorectal-cancer-stage-ii-iii-ctdna-bnt122-01-2029532055) A Multi-site, Open-label, Phase II, Randomized, Controlled Trial to Compare the Efficacy of RO7198457 Versus Watchful Waiting in Resected, Stage II (High Risk) and Stage III Colorectal Cancer Patients Who Are ctDNA Positive Following Resection **Status:** Open to Enrollment - Clinical trial ### [Metastatic Colorectal Cancer C6461003](https://www.sutterhealth.org/research/clinical-trials/metastatic-colorectal-cancer-c6461003-2080020630) AN INTERVENTIONAL, PHASE 3, DOUBLE-BLIND, RANDOMIZED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY VERSUS BEVACIZUMAB IN COMBINATION WITH CHEMOTHERAPY IN TREATMENT-NAÏVE PARTICIPANTS WITH METASTATIC COLORECTAL CANCER **Status:** Open to Enrollment - Clinical trial ### [Advanced Cervical Cancer NRG GY037](https://www.sutterhealth.org/research/clinical-trials/advanced-cervical-cancer-nrg-gy037-2097344123) A Phase III Study of Induction Pembrolizumab and Chemotherapy Followed by Chemoradiation and Pembrolizumab vs Chemoradiation and Pembrolizumab Both Followed by Pembrolizumab for High Risk Locally Advanced Cervical Cancer **Status:** Open to Enrollment - Clinical trial ### [Advanced Staged Cancer Targeted Therapy ASCO TAPUR](https://www.sutterhealth.org/research/clinical-trials/targeted-agent-and-profiling-utilization-registry-tapur-st-1049141787) Targeted Agent and Profiling Utilization Registry (TAPUR) Study **Status:** Open to Enrollment [View all clinical trials](https://www.sutterhealth.org/research-search-results?verticalKey=clinical_trial) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter 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