--- title: "Assess QOL in asthma from pt's point of view. | Sutter Health" description: "A-IQOLS is a reliable, valid, and unique assessment of the pt-perceived negative effect of asthma on their QoL, suitable for use in asthma clinical research." url: "https://www.sutterhealth.org/research/publications/assess-qol-in-asthma-pt-point-of-view-1055312418" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Research publications](https://www.sutterhealth.org/research/publications) / 4. Assess QOL in asthma from pt's point of view. # A new measure to assess asthma's impact on quality of life from the patient's perspective. Wilson SR, Mulligan MJ, Ayala E, Chausow A, Huang Q, Knowles SB, Gummidipundi S, Castro M, & Wise RA. _J Allergy Clin Immunol. pii: S0091-6749(17)30887-4. doi: 10.1016/j.jaci.2017.02.047. \[Epub ahead of print\]_ 2017-06-01 ## Abstract BACKGROUND: The Asthma Impact on Quality of Life Scale (A-IQOLS) assesses the negative effect of asthma on quality of life (QoL) from the patient's perspective, using dimensions of Flanagan's Quality of Life Scale (QOLS), a measure of current QoL. OBJECTIVES: To determine and compare the psychometric properties of the A-IQOLS and QOLS, including their sensitivities to differences and changes in asthma status. METHODS: In a test-retest design (3-5 week interval), adults with persistent asthma underwent spirometry and were administered the A-IQOLS, other asthma outcome measures (ACT, ASUI, Marks and Juniper AQLQs), and QOLS. RESULTS: Participants' (n = 147) mean age was 49 yrs.; 76% were White; 12% Hispanic; 65% female. A-IQOLS and QOLS scores were significantly correlated with other asthma outcomes scores except FEV1, but shared relatively low common variance with these measures. A-IQOLS, but not QOLS, score changes were significantly correlated with changes in asthma outcomes. The A-IQOLS SEM = 0.27 implies that a within-person score change of ≥ ±0.73 constitutes a true change. The QOLS SEM = 0.43. CONCLUSIONS: A-IQOLS provides a reliable, valid, and unique assessment of the patient-perceived negative effect of asthma on their QoL, suitable for use in asthma clinical research and potentially in clinical care. Further studies are needed in diverse patient populations. QOLS, a measure of current QoL, is less sensitive to disease status changes but may be useful in characterizing study populations, in treatment adherence research, and as a clinical and research tool in patients with multiple, severe, and/or life-limiting chronic conditions. [PubMed abstract](https://www.ncbi.nlm.nih.gov/pubmed/28579376) ## Research topics - [Asthma](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Asthma%5C%22%22) - [Health Services](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Health+Services%5C%22%22) ## Related publications [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) - Publication ### [Shared treatment decision making improves adherence and outcomes in poorly controlled asthma.](https://www.sutterhealth.org/research/publications/shared-decision-making-improves-asthma-outcomes-1055312698) Wilson SR, Strub P, Buist AS, Knowles SB, Lavori PW, Lapidus J, Vollmer WM; Better Outcomes of Asthma Treatment (BOAT) Study Group. Am J Respir Crit Care Med. 181(6):566-77. doi: 10.1164/rccm.200906-0907OC. Epub 2009 Dec 17. 2010 Mar 15 - Publication ### [Use of a motivational interviewing-informed strategy in group orientations to improve retention and intervention attendance in a randomized controlled trial..](https://www.sutterhealth.org/research/publications/motivation-interviews-grp-orient-retain-pts-1055312502) Xiao L, Lv N, Rosas LG, Karve S, Luna V, Jameiro E, Wittels N, Ma J. Health Educ Res. 31(6):729-737. Epub 2016 Oct 10. 2016 Dec 01 - Publication ### [Association of general and central obesity and atopic and nonatopic asthma in US adults.](https://www.sutterhealth.org/research/publications/obesity-atopic-nonatopic-asthma-in-us-adults-1055312601) Ma J, Xiao L. J Asthma. 50(4):395-402. doi: 10.3109/02770903.2013.770014. Epub 2013 Feb 25. 2013 May 01 - Publication ### [Adapting community based participatory research (CBPR) methods to the implementation of an asthma shared decision making intervention in ambulatory practices.](https://www.sutterhealth.org/research/publications/asthma-shared-decision-making-in-ambulatory-care-1055312730) Tapp H, Kuhn L, Alkhazraji T, Steuerwald M, Ludden T, Wilson S, Mowrer L, Mohanan S, Dulin MF. J Asthma. 51(4):380-90. doi: 10.3109/02770903.2013.876430. Epub 2014 Jan 24. 2014 May 01 - Publication ### [Shared clinician-patient decision-making about treatment of pediatric asthma: what do we know and how can we use it?](https://www.sutterhealth.org/research/publications/shared-clinician-pt-decision-making-in-ped-asthma-1055312602) Rivera-Spoljaric K, Halley M, Wilson SR. Curr Opin Allergy Clin Immunol. 14(2):161-7. doi: 10.1097/ACI.0000000000000046. 2014 Apr 01 [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]} ``` ```json {"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/publications/assess-qol-in-asthma-pt-point-of-view-1055312418#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Research publications","item":"https://www.sutterhealth.org/research/publications"},{"@type":"ListItem","position":4,"name":"Assess QOL in asthma from pt's point of view."}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalScholarlyArticle","@id":"https://www.sutterhealth.org/research/publications/assess-qol-in-asthma-pt-point-of-view-1055312418#medicalscholarlyarticle","name":"A new measure to assess asthma's impact on quality of life from the patient's perspective.","headline":"Assess QOL in asthma from pt's point of view.","abstract":"BACKGROUND: The Asthma Impact on Quality of Life Scale (A-IQOLS) assesses the negative effect of asthma on quality of life (QoL) from the patient's perspective, using dimensions of Flanagan's Quality of Life Scale (QOLS), a measure of current QoL. OBJECTIVES: To determine and compare the psychometric properties of the A-IQOLS and QOLS, including their sensitivities to differences and changes in asthma status. METHODS: In a test-retest design (3-5 week interval), adults with persistent asthma underwent spirometry and were administered the A-IQOLS, other asthma outcome measures (ACT, ASUI, Marks and Juniper AQLQs), and QOLS. RESULTS: Participants' (n = 147) mean age was 49 yrs.; 76% were White; 12% Hispanic; 65% female. A-IQOLS and QOLS scores were significantly correlated with other asthma outcomes scores except FEV1, but shared relatively low common variance with these measures. A-IQOLS, but not QOLS, score changes were significantly correlated with changes in asthma outcomes. The A-IQOLS SEM = 0.27 implies that a within-person score change of ≥ ±0.73 constitutes a true change. The QOLS SEM = 0.43. CONCLUSIONS: A-IQOLS provides a reliable, valid, and unique assessment of the patient-perceived negative effect of asthma on their QoL, suitable for use in asthma clinical research and potentially in clinical care. Further studies are needed in diverse patient populations. 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