--- title: "Comorbid chronic diseases & QoL in gyn cancer survivors. | Sutter Health" description: "Among gynecological cancer survivors, 3/4 reported at least one comorbid chronic disease. Highest prevalence was in endometrial cancer survivors." url: "https://www.sutterhealth.org/research/publications/chronic-diseases-qol-gyn-cancer-survivors-1055312386" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Research publications](https://www.sutterhealth.org/research/publications) / 4. Comorbid chronic diseases & QoL in gyn cancer survivors. # Comorbid chronic diseases and their associations with quality of life among gynecological cancer survivors. Wang JW, Sun L, Li J, Cong XH, Chen XF, Tang Z, Yu DH, Zhang TR, Luo ZN, Yuan ZP, & Yu JM. _BMC Public Health. 15:965. doi: 10.1186/s12889-015-2240-1._ 2015-09-25 ## Abstract BACKGROUND: Many gynecological cancer survivors (GCS) have comorbid chronic diseases (CCD). This study was to estimate the impacts of CCD on quality of life (QOL) in GCS. METHODS: We collected cross-sectional self-reported survey data from 598 GCS between April and July 2013, in Shanghai, China. All the subjects were asked to complete a questionnaire containing the European Organization for Research and Treatment quality of life version 3 questionnaire (EORTC QLQ-C30) and questions on socio-demographic characteristics and CCD. In order to mitigate the bias caused by confounding factors, multiple linear models were employed to calculate adjusted means of QOL scores. RESULTS: Approximately three-quarters of subjects reported at least one CCD. The highest overall prevalence of all CCD was found in endometrial cancer survivors. Subjects with CCD generally reported lower scores for most EORTC QLQ-C30 scales when compared to subjects without CCD, indicating poorer QOL, particularly for cardiovascular diseases, respiratory diseases, digestive diseases, and musculoskeletal disease. CONCLUSIONS: The CCD are common health problems among GCS. CCD have significantly negative influence on QOL, and GCS with CCD generally reported lower QOL scores. These findings suggested comprehensive cares for GCS. [PubMed abstract](https://www.ncbi.nlm.nih.gov/pubmed/?term=Wang+JW%2C+Sun+L%2C+Li+J%2C+Cong+XH%2C) ![Jiang Li, Ph.D., MPH](https://dyn.mktgcdn.com/p/H4OFJqNxBzDqkSWaIqDBiZgqIsHNsHLWdLuMd9IlNx0/fit=crop,gravity=auto,dpr=2,width=188,height=250,quality=100) Jiang Li, Ph.D., MPH Principal investigator [View profile](https://www.sutterhealth.org/research/investigators/jiang-li-phd-mph-1049681008) ## Research topics - [All Cancer](https://www.sutterhealth.org/research-search-results?query=%22%5C%22All+Cancer%5C%22%22) - [Cardiovascular Diseases](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Cardiovascular+Diseases%5C%22%22) - [Digestive Disorders](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Digestive+Disorders%5C%22%22) - [Health Services](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Health+Services%5C%22%22) - [Lung Diseases](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Lung+Diseases%5C%22%22) - [Musculoskeletal Disorders](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Musculoskeletal+Disorders%5C%22%22) - [Obstetrics and Gynecology](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Obstetrics+and+Gynecology%5C%22%22) ## Related publications [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) - Publication ### [Vocational rehabilitation of cancer patients.](https://www.sutterhealth.org/research/publications/vocational-rehabilitation-cancer-pts-1055312356) Helene G. Brown HG, Tai-Seale M. Semin Oncol Nurs. 8(3):202-211. 1992 Aug 01 - Publication ### [Patient experience shows little relationship with hospital quality management strategies.](https://www.sutterhealth.org/research/publications/pt-exp-shows-little-rel-with-hosp-qual-mgmt-1055312439) Groene O, Arah OA, Klazinga NS, Wagner C, Bartels PD, Kristensen S, Saillour F, Thompson A, Thompson CA, Pfaff H, DerSarkissian M, Sunol R. PLoS One. 10(7):e0131805. doi: 10.1371/journal.pone.0131805. eCollection 2015. 2015 Jul 07 - Publication ### [Provider perspectives on advance care planning documentation in the electronic health record.](https://www.sutterhealth.org/research/publications/providers-on-advance-care-plans-ehr-1055312324) Dillon E, Chuang J, Gupta A, Tapper S, Lai S, Yu P, Ritchie C, Tai-Seale M. Am J Hosp Palliat Care. 1049909117693578. doi: 10.1177/1049909117693578. \[Epub ahead of print\] 2017 Jan 01 - Publication ### [Precision lifestyle medicine: a new frontier in the science of behavior change and population health.](https://www.sutterhealth.org/research/publications/precision-lifestyle-medicine-1055312346) Ma J, Rosas LG, Lv N. Am J Prev Med. pii: S0749-3797(15)00638-8. doi: 10.1016/j.amepre.2015.09.035. \[Epub ahead of print\] 2015 Dec 01 - Publication ### [Exploring provider reactions to decision aid distribution and shared decision making: lessons from two specialties.](https://www.sutterhealth.org/research/publications/md-reactions-dec-aids-shared-decision-making-1055312504) Hsu C, Liss DT, Frosch DL, Westbrook EO, Arterburn D. Med Decis Making. 37(1):113-126. Epub 2016 Oct 6. 2017 Jan 01 [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]} ``` ```json {"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/publications/chronic-diseases-qol-gyn-cancer-survivors-1055312386#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Research publications","item":"https://www.sutterhealth.org/research/publications"},{"@type":"ListItem","position":4,"name":"Comorbid chronic diseases & QoL in gyn cancer survivors."}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalScholarlyArticle","@id":"https://www.sutterhealth.org/research/publications/chronic-diseases-qol-gyn-cancer-survivors-1055312386#medicalscholarlyarticle","name":"Comorbid chronic diseases and their associations with quality of life among gynecological cancer survivors.","headline":"Comorbid chronic diseases & QoL in gyn cancer survivors.","abstract":"BACKGROUND: Many gynecological cancer survivors (GCS) have comorbid chronic diseases (CCD). This study was to estimate the impacts of CCD on quality of life (QOL) in GCS. METHODS: We collected cross-sectional self-reported survey data from 598 GCS between April and July 2013, in Shanghai, China. All the subjects were asked to complete a questionnaire containing the European Organization for Research and Treatment quality of life version 3 questionnaire (EORTC QLQ-C30) and questions on socio-demographic characteristics and CCD. In order to mitigate the bias caused by confounding factors, multiple linear models were employed to calculate adjusted means of QOL scores. RESULTS: Approximately three-quarters of subjects reported at least one CCD. The highest overall prevalence of all CCD was found in endometrial cancer survivors. Subjects with CCD generally reported lower scores for most EORTC QLQ-C30 scales when compared to subjects without CCD, indicating poorer QOL, particularly for cardiovascular diseases, respiratory diseases, digestive diseases, and musculoskeletal disease. CONCLUSIONS: The CCD are common health problems among GCS. CCD have significantly negative influence on QOL, and GCS with CCD generally reported lower QOL scores. These findings suggested comprehensive cares for GCS.","description":"Among gynecological cancer survivors, 3/4 reported at least one comorbid chronic disease. Highest prevalence was in endometrial cancer survivors.","keywords":["All Cancer","Cardiovascular Diseases","Digestive Disorders","Health Services","Lung Diseases","Musculoskeletal Disorders","Obstetrics and Gynecology"],"datePublished":"2015-09-25","url":"https://www.sutterhealth.org/research/publications/chronic-diseases-qol-gyn-cancer-survivors-1055312386","inLanguage":"en-US","identifier":[{"@type":"PropertyValue","propertyID":"DOI","value":"10.1186/s12889-015-2240-1"}],"sameAs":["https://doi.org/10.1186/s12889-015-2240-1"],"isPartOf":{"@type":"Periodical","name":"BMC Public Health"},"author":[{"@type":"Person","name":"Wang JW"},{"@type":"Person","name":"Sun L"},{"@type":"Person","@id":"https://www.sutterhealth.org/research/investigators/jiang-li-phd-mph-1049681008","name":"Li J","url":"https://www.sutterhealth.org/research/investigators/jiang-li-phd-mph-1049681008"},{"@type":"Person","name":"Cong XH"},{"@type":"Person","name":"Chen XF"},{"@type":"Person","name":"Tang Z"},{"@type":"Person","name":"Yu DH"},{"@type":"Person","name":"Zhang TR"},{"@type":"Person","name":"Luo ZN"},{"@type":"Person","name":"Yuan ZP"},{"@type":"Person","name":"Yu JM"}],"sourceOrganization":{"@type":"MedicalOrganization","name":"Palo Alto Medical Foundation Research Institute"},"about":[{"@type":"DefinedTerm","name":"All Cancer","url":"https://www.sutterhealth.org/research-search-results?facets=%5B%7B%22i%22%3A%22c_researchTopics.name%22%2C%22v%22%3A%5B%22All+Cancer%22%5D%7D%5D&verticalKey=research_publication"},{"@type":"DefinedTerm","name":"Cardiovascular Diseases","url":"https://www.sutterhealth.org/research-search-results?facets=%5B%7B%22i%22%3A%22c_researchTopics.name%22%2C%22v%22%3A%5B%22Cardiovascular+Diseases%22%5D%7D%5D&verticalKey=research_publication"},{"@type":"DefinedTerm","name":"Digestive Disorders","url":"https://www.sutterhealth.org/research-search-results?facets=%5B%7B%22i%22%3A%22c_researchTopics.name%22%2C%22v%22%3A%5B%22Digestive+Disorders%22%5D%7D%5D&verticalKey=research_publication"},{"@type":"DefinedTerm","name":"Health Services","url":"https://www.sutterhealth.org/research-search-results?facets=%5B%7B%22i%22%3A%22c_researchTopics.name%22%2C%22v%22%3A%5B%22Health+Services%22%5D%7D%5D&verticalKey=research_publication"},{"@type":"DefinedTerm","name":"Lung Diseases","url":"https://www.sutterhealth.org/research-search-results?facets=%5B%7B%22i%22%3A%22c_researchTopics.name%22%2C%22v%22%3A%5B%22Lung+Diseases%22%5D%7D%5D&verticalKey=research_publication"},{"@type":"DefinedTerm","name":"Musculoskeletal Disorders","url":"https://www.sutterhealth.org/research-search-results?facets=%5B%7B%22i%22%3A%22c_researchTopics.name%22%2C%22v%22%3A%5B%22Musculoskeletal+Disorders%22%5D%7D%5D&verticalKey=research_publication"},{"@type":"DefinedTerm","name":"Obstetrics and Gynecology","url":"https://www.sutterhealth.org/research-search-results?facets=%5B%7B%22i%22%3A%22c_researchTopics.name%22%2C%22v%22%3A%5B%22Obstetrics+and+Gynecology%22%5D%7D%5D&verticalKey=research_publication"}],"mainEntityOfPage":{"@type":"WebPage","@id":"https://www.sutterhealth.org/research/publications/chronic-diseases-qol-gyn-cancer-survivors-1055312386","breadcrumb":{"@id":"https://www.sutterhealth.org/research/publications/chronic-diseases-qol-gyn-cancer-survivors-1055312386#breadcrumblist"}}} ```