--- title: "Clin, covariate phenotype data collectn: endometriosis res. | Sutter Health" description: "Std recommended and min required questionnaires focus on pelvic pain, subfertility, menstrual/reproductive history, hormone/med use, med hx, and personal info." url: "https://www.sutterhealth.org/research/publications/clin-covar-phenotype-data-collectn-endometri-res-1055312435" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Research publications](https://www.sutterhealth.org/research/publications) / 4. Clin, covariate phenotype data collectn: endometriosis res. # World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: II. Clinical and covariate phenotype data collection in endometriosis research. Vitonis AF, Vincent K, Rahmioglu N, Fassbender A, Buck Louis GM, Hummelshoj L, Giudice LC, Stratton P, Adamson GD, Becker CM, Zondervan KT, & Missmer SA; WERF EPHect Working Group. _Fertil Steril. 102(5):1223-32. doi: 10.1016/j.fertnstert.2014.07.1244. Epub 2014 Sep 22._ 2014-11-01 ## Abstract OBJECTIVE: To harmonize the collection of nonsurgical clinical and epidemiologic data relevant to endometriosis research, allowing large-scale collaboration. DESIGN: An international collaboration involving 34 clinical/academic centers and three industry collaborators from 16 countries on five continents. SETTING: In 2013, two workshops followed by global consultation, bringing together 54 leaders in endometriosis research. PATIENTS: None. INTERVENTION(S): Development of a self-administered endometriosis patient questionnaire (EPQ), based on \[1\] systematic comparison of questionnaires from eight centers that collect data from endometriosis cases (and controls/comparison women) on a medium to large scale (publication on >100 cases); \[2\] literature evidence; and \[3\] several global consultation rounds. MAIN OUTCOME MEASURE(S): Standard recommended and minimum required questionnaires to capture detailed clinical and covariate data. RESULT(S): The standard recommended (EPHect EPQ-S) and minimum required (EPHect EPQ-M) questionnaires contain questions on pelvic pain, subfertility and menstrual/reproductive history, hormone/medication use, medical history, and personal information. CONCLUSION(S): The EPQ captures the basic set of patient characteristics and exposures considered by the WERF EPHect Working Group to be most critical for the advancement of endometriosis research, but is also relevant to other female conditions with similar risk factors and/or symptomatology. The instruments will be reviewed based on feedback from investigators, and-after a first review after 1 year-triannually through systematic follow-up surveys. Updated versions will be made available through [http://endometriosisfoundation.org/ephect](http://endometriosisfoundation.org/ephect) . [PubMed abstract](http://www.ncbi.nlm.nih.gov/pubmed/25256930) ## Research topics - [Disease Management](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Disease+Management%5C%22%22) - [Obstetrics and Gynecology](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Obstetrics+and+Gynecology%5C%22%22) ## Related publications [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) - Publication ### [A randomized, controlled trial comparing the efficacy and safety of aqueous subcutaneous progesterone with vaginal progesterone for luteal phase support of in vitro fertilization.](https://www.sutterhealth.org/research/publications/aqueous-sc-progesteronevsvaginalprogesteroneinivf-1055312422) Baker VL, Jones CA, Doody K, Foulk R, Yee B, Adamson GD, Cometti B, DeVane G, Hubert G, Trevisan S, Hoehler F, Jones C, Soules M. Hum Reprod. 29(10):2212-20. doi: 10.1093/humrep/deu194. Epub 2014 Aug 6. 2014 Oct 10 - Publication ### [Improved implantation rates of day 3 embryo transfers with the use of an automated time-lapse-enabled test to aid in embryo selection.](https://www.sutterhealth.org/research/publications/improved-implantation-rates-day-3-embryo-transfers-1055312301) Adamson GD, Abusief ME, Palao L, Witmer J, Palao LM, Gvakharia M. Fertil Steril. pii: S0015-0282(15)02041-5. doi: 10.1016/j.fertnstert.2015.10.030. \[Epub ahead of print\] 2015 Nov 18 - Publication ### [International Committee for Monitoring Assisted Reproductive Technologies: World Report on Assisted Reproductive Technologies, 2007.](https://www.sutterhealth.org/research/publications/world-report-assisted-reproduct-technology-2007-1055312451) Ishihara O, Adamson GD, Dyer S, de Mouzon J, Nygren KG, Sullivan EA, Zegers-Hochschild F, Mansour R. Fertil Steril. 103(2):402-13.e11. doi: 10.1016/j.fertnstert.2014.11.004. Epub 2014 Dec 13. 2015 Feb 01 - Publication ### [A success story: impact of the United States in vitro fertilization data registry on advancing fertility care.](https://www.sutterhealth.org/research/publications/us-in-vitro-fertilization-data-registry-success-1055312413) Adamson GD. Fertil Steril. 111(3):457-458. doi: 10.1016/j.fertnstert.2019.01.031. 2019 Mar 01 - Publication ### [World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: III. Fluid biospecimen collection, processing, and storage in endometriosis research.](https://www.sutterhealth.org/research/publications/fluid-biospec-collect-process-store-endomet-res-1055312426) Rahmioglu N, Fassbender A, Vitonis AF, Tworoger SS, Hummelshoj L, D'Hooghe TM, Adamson GD, Giudice LC, Becker CM, Zondervan KT, Missmer SA; WERF EPHect Working Group. Fertil Steril. 2014 Nov;102(5):1233-43. doi: 10.1016/j.fertnstert.2014.07.1208. Epub 2014 Sep 22. 2014 Nov 01 [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]} ``` ```json {"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/publications/clin-covar-phenotype-data-collectn-endometri-res-1055312435#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Research publications","item":"https://www.sutterhealth.org/research/publications"},{"@type":"ListItem","position":4,"name":"Clin, covariate phenotype data collectn: endometriosis res."}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalScholarlyArticle","@id":"https://www.sutterhealth.org/research/publications/clin-covar-phenotype-data-collectn-endometri-res-1055312435#medicalscholarlyarticle","name":"World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: II. 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MAIN OUTCOME MEASURE(S): Standard recommended and minimum required questionnaires to capture detailed clinical and covariate data. RESULT(S): The standard recommended (EPHect EPQ-S) and minimum required (EPHect EPQ-M) questionnaires contain questions on pelvic pain, subfertility and menstrual/reproductive history, hormone/medication use, medical history, and personal information. CONCLUSION(S): The EPQ captures the basic set of patient characteristics and exposures considered by the WERF EPHect Working Group to be most critical for the advancement of endometriosis research, but is also relevant to other female conditions with similar risk factors and/or symptomatology. The instruments will be reviewed based on feedback from investigators, and-after a first review after 1 year-triannually through systematic follow-up surveys. 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