--- title: "Disparities in adherence to anti-HTN regimens. | Sutter Health" description: "Disparities were found with regard to adherence to and persistence with antihypertensive regimens." url: "https://www.sutterhealth.org/research/publications/disparities-in-adherence-to-anti-htn-regimens-1055312629" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Research publications](https://www.sutterhealth.org/research/publications) / 4. Disparities in adherence to anti-HTN regimens. # Disparities in adherence to and persistence with antihypertensive regimens: an exploratory analysis from a community-based provider network. Ishisaka DY, Jukes T, Romanelli RJ, Wong KS, & Schiro TA. _J Am Soc Hypertens. 6(3):201-9. doi: 10.1016/j.jash.2012.02.004._ 2012-05-01 ## Abstract ****Background:**** Despite the availability of effective antihypertensive therapies, adherence to and persistence with treatment is suboptimal. As such, there is a need to better understand factors associated with adherence and persistence, such as race/ethnicity. ****Methods:**** In a retrospective, exploratory analysis of 51,772 hypertensive adult subjects identified in the electronic medical record, we examined medication possession ratio and proportion of days covered as proxies for adherence and persistence, respectively. Logistic regression analyses were performed to assess the role of race/ethnicity in adherence to and persistence with antihypertensive treatments. ****Results:**** Relative to white subjects, Asian American/Pacific Islander, black, Hispanic, and "other" subjects were significantly less likely to be adherent to and persistent with their antihypertensive regimens. Black and Hispanic subjects had the lowest odds of adherence (0.46, 95% CI: 0.43-0.49 and 0.58, 95% CI: 0.54-0.62, respectively) and persistence (0.70, 95% CI: 0.65-0.75 and 0.70, 95% CI: 0.66-0.74, respectively) relative to white subjects. Other factors significantly associated with both lower adherence and persistence included younger age and lower chronic disease score. ****Conclusions:**** Disparities were found with regard to adherence to and persistence with antihypertensive regimens. Future studies should address these disparities by designing interventions to improve medication-taking behavior in high-risk populations. [PubMed abstract](http://www.ncbi.nlm.nih.gov/pubmed/22520931) ## Research topics - [Cardiovascular Diseases](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Cardiovascular+Diseases%5C%22%22) - [Disease Management](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Disease+Management%5C%22%22) - [Health Disparities](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Health+Disparities%5C%22%22) ## Related publications [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) - Publication ### [Disparities in blood pressure control within a community-based provider network: an exploratory analysis.](https://www.sutterhealth.org/research/publications/disparities-in-blood-pressure-control-1055312715) Romanelli RJ1, Schiro TA, Jukes T, Wong KS, Ishisaka DY. Ann Pharmacother. 45(12):1473-82. doi: 10.1345/aph.1Q523. Epub 2011 Dec 6. 2011 Dec 01 - Publication ### [Dyslipidemia in special ethnic populations.](https://www.sutterhealth.org/research/publications/dyslipidemia-special-ethnic-populations-1055312482) Pu J, Romanelli R, Zhao B, Azar KM, Hastings KG, Nimbal V, Fortmann SP, Palaniappan LP. Endocrinol Metab Clin North Am. 45(1):205-16. doi: 10.1016/j.ecl.2015.09.013 2016 Mar 01 - Publication ### [Case management to reduce risk of cardiovascular disease in a county health care system.](https://www.sutterhealth.org/research/publications/case-mgmt-reduce-cvd-risk-county-health-system-1055312926) Ma J, Berra K, Haskell WL, Klieman L, Hyde S, Smith MW, Xiao L, Stafford RS. 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Prev Med Rep. 8:42-50. doi: 10.1016/j.pmedr.2017.07.010. eCollection 2017 Dec. 2017 Aug 05 [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]} ``` ```json {"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/publications/disparities-in-adherence-to-anti-htn-regimens-1055312629#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Research publications","item":"https://www.sutterhealth.org/research/publications"},{"@type":"ListItem","position":4,"name":"Disparities in adherence to anti-HTN regimens."}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalScholarlyArticle","@id":"https://www.sutterhealth.org/research/publications/disparities-in-adherence-to-anti-htn-regimens-1055312629#medicalscholarlyarticle","name":"Disparities in adherence to and persistence with antihypertensive regimens: an exploratory analysis from a community-based provider network.","headline":"Disparities in adherence to anti-HTN regimens.","abstract":"Background: Despite the availability of effective antihypertensive therapies, adherence to and persistence with treatment is suboptimal. As such, there is a need to better understand factors associated with adherence and persistence, such as race/ethnicity. Methods: In a retrospective, exploratory analysis of 51,772 hypertensive adult subjects identified in the electronic medical record, we examined medication possession ratio and proportion of days covered as proxies for adherence and persistence, respectively. Logistic regression analyses were performed to assess the role of race/ethnicity in adherence to and persistence with antihypertensive treatments. Results: Relative to white subjects, Asian American/Pacific Islander, black, Hispanic, and \"other\" subjects were significantly less likely to be adherent to and persistent with their antihypertensive regimens. Black and Hispanic subjects had the lowest odds of adherence (0.46, 95% CI: 0.43-0.49 and 0.58, 95% CI: 0.54-0.62, respectively) and persistence (0.70, 95% CI: 0.65-0.75 and 0.70, 95% CI: 0.66-0.74, respectively) relative to white subjects. Other factors significantly associated with both lower adherence and persistence included younger age and lower chronic disease score. Conclusions: Disparities were found with regard to adherence to and persistence with antihypertensive regimens. 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