---
title: "Today's hepatic stellate cells: not father's sternzellen. | Sutter Health"
description: "Comment on: CD133+ hepatic stellate cells are progenitor cells. [Biochem Biophys Res Commun. 2007]"
url: "https://www.sutterhealth.org/research/publications/hepatic-stellate-cells-not-fathers-sternzellen-1055312891"
---

1.  [Home](https://www.sutterhealth.org/) /
2.  [Research](https://www.sutterhealth.org/research) /
3.  [Research publications](https://www.sutterhealth.org/research/publications) /
4.  Today's hepatic stellate cells: not father's sternzellen.

# Today's hepatic stellate cells: not your father's sternzellen.

Chan EP & Wells RG.

_Hepatology. 45(5):1326-7._

2007-05-01

## Abstract

Comment on: CD133+ hepatic stellate cells are progenitor cells. \[Biochem Biophys Res Commun. 2007\]

[PubMed abstract](http://www.ncbi.nlm.nih.gov/pubmed/17464976)

## Research topics

-   [Liver Diseases and Transplant](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Liver+Diseases+and+Transplant%5C%22%22)

## Related publications

[View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication)

-   Publication
    
    ### [Transforming growth factor-beta and substrate stiffness regulate portal fibroblast activation in culture.](https://www.sutterhealth.org/research/publications/tgf-beta-regulate-fibroblast-activation-culture-1055312985)
    
    Li Z, Dranoff JA, Chan EP, Uemura M, Sévigny J, Wells RG.
    
    Hepatology. 46(4):1246-56.
    
    2007 Oct 01
    
-   Publication
    
    ### [Hepatic stellate cells require a stiff environment for myofibroblastic differentiation.](https://www.sutterhealth.org/research/publications/hsc-stiff-env-myofibroblastic-differentiatn-1055312899)
    
    Olsen AL, Bloomer SA, Chan EP, Gaça MD, Georges PC, Sackey B, Uemura M, Janmey PA, Wells RG.
    
    Am J Physiol Gastrointest Liver Physiol. 301(1):G110-8. doi: 10.1152/ajpgi.00412.2010. Epub 2011 Apr 28.
    
    2011 Jul 01
    
-   Publication
    
    ### [Factors associated with prevalence and treatment of primary biliary cholangitis in United States health systems.](https://www.sutterhealth.org/research/publications/prevalence-tx-biliary-cholangitis-in-us-1055312312)
    
    Lu M, Li J, Haller IV, Romanelli RJ, VanWormer JJ, Rodriguez CV, Raebel MA, Boscarino JA, Schmidt MA, Daida YG, Sahota A, Vincent J, Bowlus CL, Lindor K, Rupp LB, Gordon SC; FOLD Investigators.
    
    Clin Gastroenterol Hepatol. pii: S1542-3565(17)31243-0. doi: 10.1016/j.cgh.2017.10.018. \[Epub ahead of print\]
    
    2017 Oct 21
    
-   Publication
    
    ### [Ursodeoxycholic acid treatment preferentially improves overall survival among African Americans with primary biliary cholangitis.](https://www.sutterhealth.org/research/publications/ursodeoxycholic-acid-treatment-for-biliary-cholangitis-1055312732)
    
    Gordon SC, Wu KH, Lindor K, Bowlus CL, Rodriguez CV, Anderson H, Boscarino JA, Trudeau S, Rupp LB, Haller IV, Romanelli RJ, VanWormer JJ, Schmidt MA, Daida YG, Sahota A, Vincent J, Zhang T, Li J, Lu M; FOLD Investigators.
    
    Am J Gastroenterol. 2020 Jan 27. doi: 10.14309/ajg.0000000000000512. \[Epub ahead of print\]
    
    2020 Jan 27
    
-   Publication
    
    ### [Increasing prevalence of primary biliary cholangitis and reduced mortality with treatment.](https://www.sutterhealth.org/research/publications/prevalence-and-tx-of-primary-biliary-cholangitis-in-us-1055312359)
    
    Lu M, Zhou Y, Haller IV, Romanelli RJ, VanWormer JJ, Rodriguez CV, Anderson H, Boscarino JA, Schmidt MA, Daida YG, Sahota A, Vincent J, Bowlus CL, Lindor K, Zhang T, Trudeau S, Li J, Rupp LB, Gordon SC; FOLD Investigators.
    
    Clin Gastroenterol Hepatol. pii: S1542-3565(17)31529-X. doi: 10.1016/j.cgh.2017.12.033. \[Epub ahead of print\]
    
    2017 Dec 22
    

[View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication)

```json
{"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]}
```

```json
{"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/publications/hepatic-stellate-cells-not-fathers-sternzellen-1055312891#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Research publications","item":"https://www.sutterhealth.org/research/publications"},{"@type":"ListItem","position":4,"name":"Today's hepatic stellate cells: not father's sternzellen."}]}
```

```json
{"@context":"https://schema.org","@type":"MedicalScholarlyArticle","@id":"https://www.sutterhealth.org/research/publications/hepatic-stellate-cells-not-fathers-sternzellen-1055312891#medicalscholarlyarticle","name":"Today's hepatic stellate cells: not your father's sternzellen.","headline":"Today's hepatic stellate cells: not father's sternzellen.","abstract":"Comment on: CD133+ hepatic stellate cells are progenitor cells. [Biochem Biophys Res Commun. 2007]","description":"Comment on: CD133+ hepatic stellate cells are progenitor cells. [Biochem Biophys Res Commun. 2007]","keywords":["Liver Diseases and Transplant"],"datePublished":"2007-05-01","url":"https://www.sutterhealth.org/research/publications/hepatic-stellate-cells-not-fathers-sternzellen-1055312891","inLanguage":"en-US","identifier":[{"@type":"PropertyValue","propertyID":"PMID","value":"17464976"}],"sameAs":["https://pubmed.ncbi.nlm.nih.gov/17464976/"],"isPartOf":{"@type":"Periodical","name":"Hepatology"},"author":[{"@type":"Person","name":"Chan EP"},{"@type":"Person","name":"Wells RG"}],"sourceOrganization":{"@type":"MedicalOrganization","name":"Palo Alto Medical Foundation Research Institute"},"about":[{"@type":"DefinedTerm","name":"Liver Diseases and Transplant","url":"https://www.sutterhealth.org/research-search-results?facets=%5B%7B%22i%22%3A%22c_researchTopics.name%22%2C%22v%22%3A%5B%22Liver+Diseases+and+Transplant%22%5D%7D%5D&verticalKey=research_publication"}],"mainEntityOfPage":{"@type":"WebPage","@id":"https://www.sutterhealth.org/research/publications/hepatic-stellate-cells-not-fathers-sternzellen-1055312891","breadcrumb":{"@id":"https://www.sutterhealth.org/research/publications/hepatic-stellate-cells-not-fathers-sternzellen-1055312891#breadcrumblist"}}}
```
