--- title: "Nonrigid motion correction 3D image-based navigators, ht MRA | Sutter Health" description: "We have developed a nonrigid motion-correction method based on 3D iNAVs and an autofocusing algorithm that improves the vessel sharpness of free-breathing whole-heart coronary MRA." url: "https://www.sutterhealth.org/research/publications/motion-correction-3d-image-navig-ht-mra-1055312449" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Research publications](https://www.sutterhealth.org/research/publications) / 4. Nonrigid motion correction 3D image-based navigators, ht MRA # Nonrigid motion correction with 3D image-based navigators for coronary MR angiography. Luo J, Addy NO, Ingle RR, Baron CA, Cheng JY, Hu BS, & Nishimura DG. _Magn Reson Med. doi: 10.1002/mrm.26273. \[Epub ahead of print\]_ 2016-05-13 ## Abstract PURPOSE: To develop a retrospective nonrigid motion-correction method based on 3D image-based navigators (iNAVs) for free-breathing whole-heart coronary magnetic resonance angiography (MRA). METHODS: The proposed method detects global rigid-body motion and localized nonrigid motion from 3D iNAVs and compensates them with an autofocusing algorithm. To model the global motion, 3D rotation and translation are estimated from the 3D iNAVs. Two sets of localized nonrigid motions are obtained from deformation fields between 3D iNAVs and reconstructed binned images, respectively. A bank of motion-corrected images is generated and the final image is assembled pixel-by-pixel by selecting the best focused pixel from this bank. In vivo studies with six healthy volunteers were conducted to compare the performance of the proposed method with 3D translational motion correction and no correction. RESULTS: In vivo studies showed that compared to no correction, 3D translational motion correction and the proposed method increased the vessel sharpness by 13% ± 13% and 19% ± 16%, respectively. Out of 90 vessel segments, 75 segments showed improvement with the proposed method compared to 3D translational correction. CONCLUSION: We have developed a nonrigid motion-correction method based on 3D iNAVs and an autofocusing algorithm that improves the vessel sharpness of free-breathing whole-heart coronary MRA. [PubMed abstract](http://www.ncbi.nlm.nih.gov/pubmed/27174673) ![Bob S Hu, M.D.](https://dyn.mktgcdn.com/p/OLtyV-80yDbOmh0GcQI3xnNzxEtgLP1RmJcZvvKP3u4/fit=crop,gravity=auto,dpr=2,width=188,height=250,quality=100) Bob S Hu, M.D. Principal investigator [View profile](https://www.sutterhealth.org/research/investigators/bob-s-hu-md-1049681033) ## Research topics - [Cardiovascular Diseases](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Cardiovascular+Diseases%5C%22%22) - [Disease Management](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Disease+Management%5C%22%22) ## Related publications [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) - Publication ### [Off-resonance-robust velocity-selective magnetization preparation for non-contrast-enhanced peripheral MR angiography.](https://www.sutterhealth.org/research/publications/off-reson-robust-veloc-select-magnetiz-prep-mra-1055312480) Shin T, Hu BS, Nishimura DG. Magn Reson Med. 70(5):1229-40. doi: 10.1002/mrm.24561. Epub 2012 Nov 28. 2013 Nov 01 - Publication ### [Rapid single-breath-hold 3D late gadolinium enhancement cardiac MRI using a stack-of-spirals acquisition.](https://www.sutterhealth.org/research/publications/rapid-3d-gadolinium-enhancemt-cardiac-mri-1055312461) Shin T, Lustig M, Nishimura DG, Hu BS. J Magn Reson Imaging. 40(6):1496-502. doi: 10.1002/jmri.24494. Epub 2013 Nov 15. J Magn Reson Imaging. 40(6):1496-502. doi: 10.1002/jmri.24494. Epub 2013 Nov 15. Send to: 2014 Dec 02 - Publication ### [Effect of financial incentives to physicians, patients, or both on lipid levels: a randomized clinical trial.](https://www.sutterhealth.org/research/publications/financial-md-and-pt-incentives-on-lipid-levels-1055312784) Asch DA, Troxel AB, Stewart WF, Sequist TD, Jones JB, Hirsch AG, Hoffer K, Zhu J, Wang W, Hodlofski A, Frasch AB, Weiner MG, Finnerty DD, Rosenthal MB, Gangemi K, Volpp KG. JAMA. 314(18):1926-35. doi: 10.1001/jama.2015.14850. 2015 Nov 10 - Publication ### [Non-contrast-enhanced peripheral angiography using a sliding interleaved cylinder acquisition.](https://www.sutterhealth.org/research/publications/noncontrast-enhance-periph-angiog-use-slincyl-1055312471) Kwon KT, Kerr AB, Wu HH, Hu BS, Brittain JH, Nishimura DG. Magn Reson Med. 74(3):727-38. doi: 10.1002/mrm.25452. Epub 2014 Sep 9. 2015 Sep 01 - Publication ### [Mitral valve operations through standard and smaller incisions.](https://www.sutterhealth.org/research/publications/mitral-valve-operations-std-smaller-incisions-1055312446) Gaudiani VA, Grunkemeier GL, Castro LJ, Fisher AL, Wu Y. Heart Surg Forum. 7(4):E337-42. 2004 Jan 01 [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]} ``` ```json {"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/publications/motion-correction-3d-image-navig-ht-mra-1055312449#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Research publications","item":"https://www.sutterhealth.org/research/publications"},{"@type":"ListItem","position":4,"name":"Nonrigid motion correction 3D image-based navigators, ht MRA"}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalScholarlyArticle","@id":"https://www.sutterhealth.org/research/publications/motion-correction-3d-image-navig-ht-mra-1055312449#medicalscholarlyarticle","name":"Nonrigid motion correction with 3D image-based navigators for coronary MR angiography.","headline":"Nonrigid motion correction 3D image-based navigators, ht MRA","abstract":"PURPOSE: To develop a retrospective nonrigid motion-correction method based on 3D image-based navigators (iNAVs) for free-breathing whole-heart coronary magnetic resonance angiography (MRA). METHODS: The proposed method detects global rigid-body motion and localized nonrigid motion from 3D iNAVs and compensates them with an autofocusing algorithm. To model the global motion, 3D rotation and translation are estimated from the 3D iNAVs. Two sets of localized nonrigid motions are obtained from deformation fields between 3D iNAVs and reconstructed binned images, respectively. A bank of motion-corrected images is generated and the final image is assembled pixel-by-pixel by selecting the best focused pixel from this bank. In vivo studies with six healthy volunteers were conducted to compare the performance of the proposed method with 3D translational motion correction and no correction. RESULTS: In vivo studies showed that compared to no correction, 3D translational motion correction and the proposed method increased the vessel sharpness by 13% ± 13% and 19% ± 16%, respectively. Out of 90 vessel segments, 75 segments showed improvement with the proposed method compared to 3D translational correction. CONCLUSION: We have developed a nonrigid motion-correction method based on 3D iNAVs and an autofocusing algorithm that improves the vessel sharpness of free-breathing whole-heart coronary MRA.","description":"We have developed a nonrigid motion-correction method based on 3D iNAVs and an autofocusing algorithm that improves the vessel sharpness of free-breathing whole-heart coronary MRA.","keywords":["Cardiovascular Diseases","Disease Management"],"datePublished":"2016-05-13","url":"https://www.sutterhealth.org/research/publications/motion-correction-3d-image-navig-ht-mra-1055312449","inLanguage":"en-US","identifier":[{"@type":"PropertyValue","propertyID":"PMID","value":"27174673"},{"@type":"PropertyValue","propertyID":"DOI","value":"10.1002/mrm.26273"}],"sameAs":["https://pubmed.ncbi.nlm.nih.gov/27174673/","https://doi.org/10.1002/mrm.26273"],"isPartOf":{"@type":"Periodical","name":"Magn Reson Med"},"author":[{"@type":"Person","name":"Luo J"},{"@type":"Person","name":"Addy NO"},{"@type":"Person","name":"Ingle RR"},{"@type":"Person","name":"Baron CA"},{"@type":"Person","name":"Cheng JY"},{"@type":"Person","@id":"https://www.sutterhealth.org/research/investigators/bob-s-hu-md-1049681033","name":"Hu BS","url":"https://www.sutterhealth.org/research/investigators/bob-s-hu-md-1049681033"},{"@type":"Person","name":"Nishimura DG"}],"sourceOrganization":{"@type":"MedicalOrganization","name":"Palo Alto Medical Foundation Research Institute"},"about":[{"@type":"DefinedTerm","name":"Cardiovascular Diseases","url":"https://www.sutterhealth.org/research-search-results?facets=%5B%7B%22i%22%3A%22c_researchTopics.name%22%2C%22v%22%3A%5B%22Cardiovascular+Diseases%22%5D%7D%5D&verticalKey=research_publication"},{"@type":"DefinedTerm","name":"Disease Management","url":"https://www.sutterhealth.org/research-search-results?facets=%5B%7B%22i%22%3A%22c_researchTopics.name%22%2C%22v%22%3A%5B%22Disease+Management%22%5D%7D%5D&verticalKey=research_publication"}],"mainEntityOfPage":{"@type":"WebPage","@id":"https://www.sutterhealth.org/research/publications/motion-correction-3d-image-navig-ht-mra-1055312449","breadcrumb":{"@id":"https://www.sutterhealth.org/research/publications/motion-correction-3d-image-navig-ht-mra-1055312449#breadcrumblist"}}} ```