--- title: "Neuropsychiatric update: neuroimaging | Sutter Health" description: "Neuropsychiatric update: neuroimaging schizophrenia." url: "https://www.sutterhealth.org/research/publications/neuropsychiatric-update-neuroimaging-1055312750" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Research publications](https://www.sutterhealth.org/research/publications) / 4. Neuropsychiatric update: neuroimaging # Neuropsychiatric update: neuroimaging schizophrenia. Psychopharmacol Bull. 2007;40(4):156-67. Neuropsychiatric update: neuroimaging schizophrenia. Kile SJ. _Psychopharmacol Bull. 2007;40(4):156-67. Neuropsychiatric update: neuroimaging schizophrenia. Kile SJ._ 2007-07-20 ## Abstract Abstract Neuroimaging has revitalized the quest for the neurobiology of schizophrenia. The various neuroimaging modalities used in research are described including CT, MRI, PET, SPECT, fMRI, and DTI. Prominent and consistent neuroanatomical findings in the neuroimaging literature of schizophrenia are outlined. These findings, including enlargement of the lateral ventricles, undersized superior temporal gyrus, and prefrontal abnormalities, are supported with neuropathological studies of schizophrenia. Additionally, these findings are correlated with the clinical symptoms of schizophrenia. Neurochemical imaging studies of schizophrenia are reviewed and noted to support dopaminergic dysregulation consistent with the dopamine hypothesis. Finally, current and near-future clinical uses of neuroimaging are described. PMID:18227785\[PubMed - indexed for MEDLINE\] [PubMed abstract](http://www.ncbi.nlm.nih.gov/pubmed/18227785) ![Shawn J Kile, M.D.](https://dyn.mktgcdn.com/p/q0wjBudDBEScUW_Fehb6xrCnhqVyTm2ZGn3nY5fkqXc/fit=crop,gravity=auto,dpr=2,width=188,height=250,quality=100) Shawn J Kile, M.D. Principal investigator [View profile](https://www.sutterhealth.org/research/investigators/shawn-j-kile-md-1049681124) ## Research topics - [Neurological Disorders](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Neurological+Disorders%5C%22%22) ## Related publications [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) - Publication ### [Brain regions showing increased activation by threat-related words in panic disorder.](https://www.sutterhealth.org/research/publications/brainregionsshowingincreasedactivation-1055312756) Maddock RJ1, Buonocore MH, Kile SJ, Garrett AS. Author information 1Department of Radiology, University of California Davis, 4801 X St, Sacramento, California 95817, USA. rjmaddock@ucdaris.edu Neuroreport. 2003 Mar 2003 Mar 20 - Publication ### [Prevalence of migraine in a diverse community--electronic methods for migraine ascertainment in a large integrated health plan.](https://www.sutterhealth.org/research/publications/migraine-prevalence-through-ehrs-large-health-plan-1055312704) Pressman A, Jacobson A, Eguilos R, Gelfand A, Huynh C, Hamilton L, Avins A, Bakshi N, Merikangas K. Cephalalgia. 36(4):325-34. doi: 10.1177/0333102415590242. Epub 2015 Jun 11. 2016 Apr 01 - Publication ### [Identification of short-term pharmacodynamic effects of interferon-beta-1a in multiple sclerosis subjects with broad- based phenotypic profiling.](https://www.sutterhealth.org/research/publications/pharmacodynamic-effects-interferon-beta-1a-ms-1055312290) Kantor AB, Deng J, Waubant E, Lin H, Becker CH, Lacy JR, Perrone AM, Bennett D, Goelz SE. J Neuroimmunol. 188(1-2):103-16. Epub 2007 Jul 5. 2007 Aug 01 - Publication ### [New and sex-specific migraine susceptibility loci identified from a multiethnic genome-wide meta-analysis](https://www.sutterhealth.org/research/publications/new-sex-specific-migraine-susceptibility-1055312836) Choquet H, Yin J, Jacobson AS, Horton BH, Hoffmann TJ, Jorgenson E, Avins AL, Pressman AR Commun Biol.4(1):864. doi: 10.1038/s42003-021-02356-y. 2021 Jul 22 - Publication ### [Alzheimer abnormalities of the amygdala with Klüver-Bucy syndrome symptoms: an amygdaloid variant of Alzheimer disease](https://www.sutterhealth.org/research/publications/alzheimer-abnormalities-of-the-amygdala-1055312743) Arch Neurol. 2009 Jan;66(1):125-9. doi: 10.1001/archneurol.2008.517. Alzheimer abnormalities of the amygdala with Klüver-Bucy syndrome symptoms: an amygdaloid variant of Alzheimer disease. Kile SJ1, Ellis WG, Olichney JM, Farias S, DeCarli C. Author information 1Department of Neurology, University of California at Davis Arch Neurol. 2009 Jan; 2009 Jan 20 [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]} ``` ```json {"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/publications/neuropsychiatric-update-neuroimaging-1055312750#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Research publications","item":"https://www.sutterhealth.org/research/publications"},{"@type":"ListItem","position":4,"name":"Neuropsychiatric update: neuroimaging"}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalScholarlyArticle","@id":"https://www.sutterhealth.org/research/publications/neuropsychiatric-update-neuroimaging-1055312750#medicalscholarlyarticle","name":"Neuropsychiatric update: neuroimaging schizophrenia.","headline":"Neuropsychiatric update: neuroimaging","abstract":"Abstract Neuroimaging has revitalized the quest for the neurobiology of schizophrenia. 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