--- title: "Noncontrast-enhanced periph angiog use sliding cyl acquis | Sutter Health" description: "Non-contrast-enhanced angiography using SLINCYL can provide angiograms with improved artery-vein contrast in the lower extremities." url: "https://www.sutterhealth.org/research/publications/noncontrast-enhance-periph-angiog-use-slincyl-1055312471" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Research publications](https://www.sutterhealth.org/research/publications) / 4. Noncontrast-enhanced periph angiog use sliding cyl acquis # Non-contrast-enhanced peripheral angiography using a sliding interleaved cylinder acquisition. Kwon KT, Kerr AB, Wu HH, Hu BS, Brittain JH, & Nishimura DG. _Magn Reson Med. 74(3):727-38. doi: 10.1002/mrm.25452. Epub 2014 Sep 9._ 2015-09-01 ## Abstract PURPOSE: To develop a new sequence for non-contrast-enhanced peripheral angiography using a sliding interleaved cylinder (SLINCYL) acquisition. METHODS: A venous saturation pulse was incorporated into a three-dimensional magnetization-prepared balanced steady-state free precession sequence for non-contrast-enhanced peripheral angiography to improve artery-vein contrast. The SLINCYL acquisition, which consists of a series of overlapped thin slabs for volumetric coverage similar to the original sliding interleaved ky (SLINKY) acquisition, was used to evenly distribute the venous-suppression effects over the field of view. In addition, the thin-slab-scan nature of SLINCYL and the centric-ordered sampling geometry of its readout trajectory were exploited to implement efficient fluid-suppression and parallel imaging schemes. The sequence was tested in healthy subjects and a patient. RESULTS: Compared to a multiple overlapped thin slab acquisition, both SLINKY and SLINCYL suppressed the venetian blind artifacts and provided similar artery-vein contrast. However, SLINCYL achieved this with shorter scan times and less noticeable artifacts from k-space amplitude modulation than SLINKY. The fluid-suppression and parallel imaging schemes were also validated. A patient study using the SLINCYL-based sequence well identified stenoses at the superficial femoral arteries, which were also confirmed with digital subtraction angiography. CONCLUSION: Non-contrast-enhanced angiography using SLINCYL can provide angiograms with improved artery-vein contrast in the lower extremities. [PubMed abstract](http://www.ncbi.nlm.nih.gov/pubmed/25203505) ![Bob S Hu, M.D.](https://dyn.mktgcdn.com/p/OLtyV-80yDbOmh0GcQI3xnNzxEtgLP1RmJcZvvKP3u4/fit=crop,gravity=auto,dpr=2,width=188,height=250,quality=100) Bob S Hu, M.D. Principal investigator [View profile](https://www.sutterhealth.org/research/investigators/bob-s-hu-md-1049681033) ## Research topics - [Cardiovascular Diseases](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Cardiovascular+Diseases%5C%22%22) - [Disease Management](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Disease+Management%5C%22%22) ## Related publications [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) - Publication ### [Rapid single-breath-hold 3D late gadolinium enhancement cardiac MRI using a stack-of-spirals acquisition.](https://www.sutterhealth.org/research/publications/rapid-3d-gadolinium-enhancemt-cardiac-mri-1055312461) Shin T, Lustig M, Nishimura DG, Hu BS. J Magn Reson Imaging. 40(6):1496-502. doi: 10.1002/jmri.24494. Epub 2013 Nov 15. J Magn Reson Imaging. 40(6):1496-502. doi: 10.1002/jmri.24494. Epub 2013 Nov 15. Send to: 2014 Dec 02 - Publication ### [Nonrigid autofocus motion correction for coronary MR angiography with a 3D cones trajectory.](https://www.sutterhealth.org/research/publications/nonrigid-autofocus-motion-correctn-ht-mra-1055312469) Ingle RR, Wu HH, Addy NO, Cheng JY, Yang PC, Hu BS, Nishimura DG. Magn Reson Med. 72(2):347-61. doi: 10.1002/mrm.24924. Epub 2013 Sep 4. 2014 Aug 01 - Publication ### [3D image-based navigators for coronary MR angiography.](https://www.sutterhealth.org/research/publications/3d-image-navig-ht-mr-angiography-1055312459) Addy NO, Ingle RR, Luo J, Baron CA, Yang PC, Hu BS, Nishimura DG. Magn Reson Med. doi: 10.1002/mrm.26269. \[Epub ahead of print\] 2016 May 13 - Publication ### [Mitral valve operations through standard and smaller incisions.](https://www.sutterhealth.org/research/publications/mitral-valve-operations-std-smaller-incisions-1055312446) Gaudiani VA, Grunkemeier GL, Castro LJ, Fisher AL, Wu Y. Heart Surg Forum. 7(4):E337-42. 2004 Jan 01 - Publication ### [Effect of financial incentives to physicians, patients, or both on lipid levels: a randomized clinical trial.](https://www.sutterhealth.org/research/publications/financial-md-and-pt-incentives-on-lipid-levels-1055312784) Asch DA, Troxel AB, Stewart WF, Sequist TD, Jones JB, Hirsch AG, Hoffer K, Zhu J, Wang W, Hodlofski A, Frasch AB, Weiner MG, Finnerty DD, Rosenthal MB, Gangemi K, Volpp KG. JAMA. 314(18):1926-35. doi: 10.1001/jama.2015.14850. 2015 Nov 10 [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]} ``` ```json {"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/publications/noncontrast-enhance-periph-angiog-use-slincyl-1055312471#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Research publications","item":"https://www.sutterhealth.org/research/publications"},{"@type":"ListItem","position":4,"name":"Noncontrast-enhanced periph angiog use sliding cyl acquis"}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalScholarlyArticle","@id":"https://www.sutterhealth.org/research/publications/noncontrast-enhance-periph-angiog-use-slincyl-1055312471#medicalscholarlyarticle","name":"Non-contrast-enhanced peripheral angiography using a sliding interleaved cylinder acquisition.","headline":"Noncontrast-enhanced periph angiog use sliding cyl acquis","abstract":"PURPOSE: To develop a new sequence for non-contrast-enhanced peripheral angiography using a sliding interleaved cylinder (SLINCYL) acquisition. METHODS: A venous saturation pulse was incorporated into a three-dimensional magnetization-prepared balanced steady-state free precession sequence for non-contrast-enhanced peripheral angiography to improve artery-vein contrast. The SLINCYL acquisition, which consists of a series of overlapped thin slabs for volumetric coverage similar to the original sliding interleaved ky (SLINKY) acquisition, was used to evenly distribute the venous-suppression effects over the field of view. In addition, the thin-slab-scan nature of SLINCYL and the centric-ordered sampling geometry of its readout trajectory were exploited to implement efficient fluid-suppression and parallel imaging schemes. The sequence was tested in healthy subjects and a patient. RESULTS: Compared to a multiple overlapped thin slab acquisition, both SLINKY and SLINCYL suppressed the venetian blind artifacts and provided similar artery-vein contrast. However, SLINCYL achieved this with shorter scan times and less noticeable artifacts from k-space amplitude modulation than SLINKY. The fluid-suppression and parallel imaging schemes were also validated. A patient study using the SLINCYL-based sequence well identified stenoses at the superficial femoral arteries, which were also confirmed with digital subtraction angiography. 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