--- title: "Obesity status modifies DPP program for wt mgmt | Sutter Health" description: "To examine whether baseline obesity severity modifies the effects of two different, primary care-based, technology-enhanced lifestyle interventions among overweight or obese adults with prediabetes and/or metabolic syndrome." url: "https://www.sutterhealth.org/research/publications/obesity-status-modifies-dpp-program-for-wt-mgmt-1055312603" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Research publications](https://www.sutterhealth.org/research/publications) / 4. Obesity status modifies DPP program for wt mgmt # Baseline obesity status modifies effectiveness of adapted diabetes prevention program lifestyle interventions for weight management in primary care. Azar KM, Xiao L, & Ma J. _Biomed Res Int. 2013:191209. doi: 10.1155/2013/191209. Epub 2013 Dec 4._ 2013-12-04 ## Abstract OBJECTIVE: To examine whether baseline obesity severity modifies the effects of two different, primary care-based, technology-enhanced lifestyle interventions among overweight or obese adults with prediabetes and/or metabolic syndrome. PATIENTS AND METHODS: We compared mean differences in changes from baseline to 15 months in clinical measures of general and central obesity among participants randomized to usual care alone (n = 81) or usual care plus a coach-led group (n = 79) or self-directed individual (n = 81) intervention, stratified by baseline body mass index (BMI) category. RESULTS: Participants with baseline BMI 35+ had greater reductions in mean BMI, body weight (as percentage change), and waist circumference in the coach-led group intervention, compared to usual care and the self-directed individual intervention (P < 0.05 for all). In contrast, the self-directed intervention was more effective than usual care only among participants with baseline BMIs between 25 ≤ 35. Mean weight loss exceeded 5% in the coach-led intervention regardless of baseline BMI category, but this was achieved only among self-directed intervention participants with baseline BMIs <35. CONCLUSIONS: Baseline BMI may influence behavioral weight-loss treatment effectiveness. Researchers and clinicians should take an individual's baseline BMI into account when developing or recommending lifestyle focused treatment strategy. This trial is registered with ClinicalTrials.gov NCT00842426. [PubMed abstract](http://www.ncbi.nlm.nih.gov/pubmed/24369008) ![Kristen M J Azar, RN, MSN, MPH](https://dyn.mktgcdn.com/p/rFmyR1kiX8JzE5-XNwup0gVC1GRaVTlH7oSDlG0Tr5A/fit=crop,gravity=auto,dpr=2,width=188,height=250,quality=100) Kristen M J Azar, RN, MSN, MPH Principal investigator [View profile](https://www.sutterhealth.org/research/investigators/kristen-m-j-azar-rn-msn-mph-1049680985) ## Research topics - [Diabetes, Insulin Resistance and Metabolic Syndrome](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Diabetes%2C+Insulin+Resistance+and+Metabolic+Syndrome%5C%22%22) - [Disease Management](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Disease+Management%5C%22%22) - [Obesity](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Obesity%5C%22%22) ## Related publications [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) - Publication ### [Two-year weight-loss maintenance in primary care-based Diabetes Prevention Program lifestyle interventions.](https://www.sutterhealth.org/research/publications/two-yr-wt-loss-maintenance-in-diabetes-program-1055312744) Xiao L, Yank V, Wilson SR, Lavori PW, Ma J. Nutr Diabetes. 3:e76. doi: 10.1038/nutd.2013.17. 2013 Jun 24 - Publication ### [Baseline reach and adoption characteristics in a randomized controlled trial of two weight loss interventions translated into primary care: A structured report of real-world applicability](https://www.sutterhealth.org/research/publications/weight-loss-interventions-translated-into-pc-1055312588) Yank V, Stafford RS, Rosas LG, Ma J. Contemp Clin Trials. 34(1):126-35. doi: 10.1016/j.cct.2012.10.007. Epub 2012 Oct 31. 2013 Jan 01 - Publication ### [Short-term weight loss patterns, baseline predictors, and longer-term follow-up within a randomized controlled trial.](https://www.sutterhealth.org/research/publications/short-term-wt-loss-patterns-in-dpp-intervention-1055312751) Yank V, Xiao L, Wilson SR, Stafford RS, Rosas LG, Ma J. Obesity (Silver Spring). 22(1):45-51. doi: 10.1002/oby.20510. Epub 2013 Oct 15. 2014 Jan 01 - Publication ### [Impact of education on weight in newly diagnosed type 2 diabetes: every little bit helps.](https://www.sutterhealth.org/research/publications/education-impact-wt-diabetes-1055312810) Azar KM, Chung S, Wang EJ, Zhao B, Linde RB, Lederer J, Palaniappan LP. PLoS One. 10(6):e0129348. doi: 10.1371/journal.pone.0129348. eCollection 2015. 2015 Jun 08 - Publication ### [Translating an evidence-based lifestyle intervention program into primary care: lessons learned.](https://www.sutterhealth.org/research/publications/translate-lifestyle-program-in-primary-care-1055312592) Blonstein AC, Yank V, Stafford RS, Wilson SR, Rosas LG, Ma J. Health Promot Pract. 14(4):491-7. doi: 10.1177/1524839913481604. Epub 2013 Mar 28. 2013 Jul 01 [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]} ``` ```json {"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/publications/obesity-status-modifies-dpp-program-for-wt-mgmt-1055312603#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Research publications","item":"https://www.sutterhealth.org/research/publications"},{"@type":"ListItem","position":4,"name":"Obesity status modifies DPP program for wt mgmt"}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalScholarlyArticle","@id":"https://www.sutterhealth.org/research/publications/obesity-status-modifies-dpp-program-for-wt-mgmt-1055312603#medicalscholarlyarticle","name":"Baseline obesity status modifies effectiveness of adapted diabetes prevention program lifestyle interventions for weight management in primary care.","headline":"Obesity status modifies DPP program for wt mgmt","abstract":"OBJECTIVE: To examine whether baseline obesity severity modifies the effects of two different, primary care-based, technology-enhanced lifestyle interventions among overweight or obese adults with prediabetes and/or metabolic syndrome. PATIENTS AND METHODS: We compared mean differences in changes from baseline to 15 months in clinical measures of general and central obesity among participants randomized to usual care alone (n = 81) or usual care plus a coach-led group (n = 79) or self-directed individual (n = 81) intervention, stratified by baseline body mass index (BMI) category. RESULTS: Participants with baseline BMI 35+ had greater reductions in mean BMI, body weight (as percentage change), and waist circumference in the coach-led group intervention, compared to usual care and the self-directed individual intervention (P \u003c 0.05 for all). In contrast, the self-directed intervention was more effective than usual care only among participants with baseline BMIs between 25 ≤ 35. Mean weight loss exceeded 5% in the coach-led intervention regardless of baseline BMI category, but this was achieved only among self-directed intervention participants with baseline BMIs \u003c35. CONCLUSIONS: Baseline BMI may influence behavioral weight-loss treatment effectiveness. Researchers and clinicians should take an individual's baseline BMI into account when developing or recommending lifestyle focused treatment strategy. This trial is registered with ClinicalTrials.gov NCT00842426.","description":"To examine whether baseline obesity severity modifies the effects of two different, primary care-based, technology-enhanced lifestyle interventions among overweight or obese adults with prediabetes and/or metabolic syndrome.","keywords":["Diabetes, Insulin Resistance and Metabolic Syndrome","Disease Management","Obesity"],"datePublished":"2013-12-04","url":"https://www.sutterhealth.org/research/publications/obesity-status-modifies-dpp-program-for-wt-mgmt-1055312603","inLanguage":"en-US","identifier":[{"@type":"PropertyValue","propertyID":"PMID","value":"24369008"},{"@type":"PropertyValue","propertyID":"DOI","value":"10.1155/2013/191209"}],"sameAs":["https://pubmed.ncbi.nlm.nih.gov/24369008/","https://doi.org/10.1155/2013/191209"],"isPartOf":{"@type":"Periodical","name":"Biomed Res Int"},"author":[{"@type":"Person","@id":"https://www.sutterhealth.org/research/investigators/kristen-m-j-azar-rn-msn-mph-1049680985","name":"Azar KM","url":"https://www.sutterhealth.org/research/investigators/kristen-m-j-azar-rn-msn-mph-1049680985"},{"@type":"Person","name":"Xiao L"},{"@type":"Person","name":"Ma J"}],"sourceOrganization":{"@type":"MedicalOrganization","name":"Palo Alto Medical Foundation Research Institute"},"about":[{"@type":"DefinedTerm","name":"Diabetes, Insulin Resistance and Metabolic Syndrome","url":"https://www.sutterhealth.org/research-search-results?facets=%5B%7B%22i%22%3A%22c_researchTopics.name%22%2C%22v%22%3A%5B%22Diabetes%2C+Insulin+Resistance+and+Metabolic+Syndrome%22%5D%7D%5D&verticalKey=research_publication"},{"@type":"DefinedTerm","name":"Disease Management","url":"https://www.sutterhealth.org/research-search-results?facets=%5B%7B%22i%22%3A%22c_researchTopics.name%22%2C%22v%22%3A%5B%22Disease+Management%22%5D%7D%5D&verticalKey=research_publication"},{"@type":"DefinedTerm","name":"Obesity","url":"https://www.sutterhealth.org/research-search-results?facets=%5B%7B%22i%22%3A%22c_researchTopics.name%22%2C%22v%22%3A%5B%22Obesity%22%5D%7D%5D&verticalKey=research_publication"}],"mainEntityOfPage":{"@type":"WebPage","@id":"https://www.sutterhealth.org/research/publications/obesity-status-modifies-dpp-program-for-wt-mgmt-1055312603","breadcrumb":{"@id":"https://www.sutterhealth.org/research/publications/obesity-status-modifies-dpp-program-for-wt-mgmt-1055312603#breadcrumblist"}}} ```