--- title: "Pilot study of DASH diet in uncontrolled asthma. | Sutter Health" description: "Pilot study aims to determine efficacy of DASH diet in adults with uncontrolled asthma." url: "https://www.sutterhealth.org/research/publications/pilot-study-of-dash-diet-in-uncontrolled-asthma-1055312757" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Research publications](https://www.sutterhealth.org/research/publications) / 4. Pilot study of DASH diet in uncontrolled asthma. # DASH for asthma: a pilot study of the DASH diet in not-well-controlled adult asthma. Ma J, Strub P, Lavori PW, Buist AS, Camargo CA Jr, Nadeau KC, Wilson SR, & Xiao L. _Contemp Clin Trials. 35(2):55-67. doi: 10.1016/j.cct.2013.04.008. Epub 2013 May 3._ 2013-07-01 ## Abstract This pilot study aims to provide effect size confidence intervals, clinical trial and intervention feasibility data, and procedural materials for a full-scale randomized controlled trial that will determine the efficacy of Dietary Approaches to Stop Hypertension (DASH) as adjunct therapy to standard care for adults with uncontrolled asthma. The DASH diet encompasses foods (e.g., fresh fruit, vegetables, and nuts) and antioxidant nutrients (e.g., vitamins A, C, E, and zinc) with potential benefits for persons with asthma, but it is unknown whether the whole diet is beneficial. Participants (n = 90) will be randomized to receive usual care alone or combined with a DASH intervention consisting of 8 group and 3 individual sessions during the first 3 months, followed by at least monthly phone consultations for another 3 months. Follow-up assessments will occur at 3 and 6 months. The primary outcome measure is the 7-item Juniper Asthma Control Questionnaire, a validated composite measure of daytime and nocturnal symptoms, activity limitations, rescue medication use, and percentage predicted forced expiratory volume in 1 second. We will explore changes in inflammatory markers important to asthma pathophysiology (e.g., fractional exhaled nitric oxide) and their potential to mediate the intervention effect on disease control. We will also conduct pre-specified subgroup analyses by genotype (e.g., polymorphisms on the glutathione S transferase gene) and phenotype (e.g., atopy, obesity). By evaluating a dietary pattern approach to improving asthma control, this study could advance the evidence base for refining clinical guidelines and public health recommendations regarding the role of dietary modifications in asthma management. [PubMed abstract](http://www.ncbi.nlm.nih.gov/pubmed/23648395) ## Research topics - [Asthma](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Asthma%5C%22%22) - [Disease Management](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Disease+Management%5C%22%22) - [Food and Nutrition](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Food+and+Nutrition%5C%22%22) - [Health Services](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Health+Services%5C%22%22) ## Related publications [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) - Publication ### [Adapting community based participatory research (CBPR) methods to the implementation of an asthma shared decision making intervention in ambulatory practices.](https://www.sutterhealth.org/research/publications/asthma-shared-decision-making-in-ambulatory-care-1055312730) Tapp H, Kuhn L, Alkhazraji T, Steuerwald M, Ludden T, Wilson S, Mowrer L, Mohanan S, Dulin MF. J Asthma. 51(4):380-90. doi: 10.3109/02770903.2013.876430. Epub 2014 Jan 24. 2014 May 01 - Publication ### [Use of dietary supplements among US adults with asthma.](https://www.sutterhealth.org/research/publications/dietary-supplements-adults-asthma-1055312968) Ma J, Xiao L. Nutr Dietary Suppl. 2011(3):9—18. 2011 Jan 12 - Publication ### [Use of a motivational interviewing-informed strategy in group orientations to improve retention and intervention attendance in a randomized controlled trial..](https://www.sutterhealth.org/research/publications/motivation-interviews-grp-orient-retain-pts-1055312502) Xiao L, Lv N, Rosas LG, Karve S, Luna V, Jameiro E, Wittels N, Ma J. Health Educ Res. 31(6):729-737. Epub 2016 Oct 10. 2016 Dec 01 - Publication ### [Shared clinician-patient decision-making about treatment of pediatric asthma: what do we know and how can we use it?](https://www.sutterhealth.org/research/publications/shared-clinician-pt-decision-making-in-ped-asthma-1055312602) Rivera-Spoljaric K, Halley M, Wilson SR. Curr Opin Allergy Clin Immunol. 14(2):161-7. doi: 10.1097/ACI.0000000000000046. 2014 Apr 01 - Publication ### [Acceptability and feasibility of the 'DASH for Asthma' intervention in a randomized controlled trial pilot study.](https://www.sutterhealth.org/research/publications/feasibility-dash-for-asthma-intervention-study-1055312344) Blonstein AC, Lv N, Camargo CA, Wilson SR, Buist AS, Rosas LG, Strub P, Ma J. Public Health Nutr. 2015 Dec 10:1-11. \[Epub ahead of print\] 2015 Dec 10 [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]} ``` ```json {"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/publications/pilot-study-of-dash-diet-in-uncontrolled-asthma-1055312757#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Research publications","item":"https://www.sutterhealth.org/research/publications"},{"@type":"ListItem","position":4,"name":"Pilot study of DASH diet in uncontrolled asthma."}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalScholarlyArticle","@id":"https://www.sutterhealth.org/research/publications/pilot-study-of-dash-diet-in-uncontrolled-asthma-1055312757#medicalscholarlyarticle","name":"DASH for asthma: a pilot study of the DASH diet in not-well-controlled adult asthma.","headline":"Pilot study of DASH diet in uncontrolled asthma.","abstract":"This pilot study aims to provide effect size confidence intervals, clinical trial and intervention feasibility data, and procedural materials for a full-scale randomized controlled trial that will determine the efficacy of Dietary Approaches to Stop Hypertension (DASH) as adjunct therapy to standard care for adults with uncontrolled asthma. The DASH diet encompasses foods (e.g., fresh fruit, vegetables, and nuts) and antioxidant nutrients (e.g., vitamins A, C, E, and zinc) with potential benefits for persons with asthma, but it is unknown whether the whole diet is beneficial. Participants (n = 90) will be randomized to receive usual care alone or combined with a DASH intervention consisting of 8 group and 3 individual sessions during the first 3 months, followed by at least monthly phone consultations for another 3 months. Follow-up assessments will occur at 3 and 6 months. The primary outcome measure is the 7-item Juniper Asthma Control Questionnaire, a validated composite measure of daytime and nocturnal symptoms, activity limitations, rescue medication use, and percentage predicted forced expiratory volume in 1 second. We will explore changes in inflammatory markers important to asthma pathophysiology (e.g., fractional exhaled nitric oxide) and their potential to mediate the intervention effect on disease control. We will also conduct pre-specified subgroup analyses by genotype (e.g., polymorphisms on the glutathione S transferase gene) and phenotype (e.g., atopy, obesity). 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