--- title: "Stress vs urgency UI and effect on QOL. | Sutter Health" description: "Estimate the impact of stress vs. urgency UI on QOL, and to determine whether the impact varies according to UI severity." url: "https://www.sutterhealth.org/research/publications/stress-vs-urgency-ui-and-effect-on-qol-1055312598" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Research publications](https://www.sutterhealth.org/research/publications) / 4. Stress vs urgency UI and effect on QOL. # The interaction of stress and urgency urinary incontinence and its effect on quality of life. Minassian VA, Sun H, Yan XS, Clarke DN, & Stewart WF. _Int Urogynecol J. 26(2):269-76. doi: 10.1007/s00192-014-2505-8. Epub 2014 Oct 3._ 2015-02-01 ## Abstract INTRODUCTION AND HYPOTHESIS: The objective was to estimate the impact of stress and urgency urinary incontinence (UI) on the quality of life (QOL), and to determine whether the impact varies according to UI severity. METHODS: We used data from the General Longitudinal Overactive Bladder Evaluation-UI study in women. Stress and urgency UI symptom severity scores ranged from 0 to 8. We used logistic regression to test the relation among different severity levels of stress and urgency UI, and their interaction with the Incontinence Impact Questionnaire (IIQ-7). This was categorized according to percentage ranges as 0-40% (reference), 41-80%, and 81-100%. RESULTS: Both stress and urgency UI were significantly associated with IIQ-7. Higher scores had higher odds ratios (ORs). The OR for urgency vs stress UI was greater at the same severity level. For instance, comparing IIQ-7 quintiles (0-40% vs 41-80%), the OR for an association with an urgency UI score of 5-6 was 5.27 (95% CI = 3.78-7.33) vs 2.76 (95% CI = 2.07-3.68) for a stress UI score of 5-6. Both UI subtypes were more strongly related to the upper (81-100%) than the to the lower (41-80%) quintiles. There was a strong positive urgency UI and stress UI interaction with the upper (i.e., 81-100%) but not the two next lower (41-80%) quintiles. CONCLUSION: The impact of UI subtypes on QOL varies according to the score of IIQ-7, stress and urgency UI, and their interaction. Urgency vs stress UI has a stronger impact. The effect is greatest for high IIQ-7 scores with a significant share mediated by the interaction of the two UI subtypes. [PubMed abstract](https://www.ncbi.nlm.nih.gov/pubmed/25278207) ![Xiaowei (Sherry) Yan, Ph.D.](https://dyn.mktgcdn.com/p/NTWox_hkmxIRiqJEc5PXKeBkfR_WMtpSQbEI4J69Xls/fit=crop,gravity=auto,dpr=2,width=188,height=250,quality=100) Xiaowei (Sherry) Yan, Ph.D. Principal investigator [View profile](https://www.sutterhealth.org/research/investigators/xiaowei-sherry-yan-phd-1049681042) ## Research topics - [Women's Health](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Women%27s+Health%5C%22%22) - [Urologic Diseases](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Urologic+Diseases%5C%22%22) ## Related publications [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) - Publication ### [Mixed incontinence masked as stress induced urgency urinary incontinence.](https://www.sutterhealth.org/research/publications/mixed-incontinence-masked-as-stress-induced-urgency-ui-1055312723) Minassian VA, Yan XS, Pitcavage J, Stewart WF. J Urol. 196(4):1190-5. doi: 10.1016/j.juro.2016.04.084. Epub 2016 May 6. 2016 Oct 01 - Publication ### [Does transition of urinary incontinence from one subtype to another represent progression of the disease?](https://www.sutterhealth.org/research/publications/urinary-incontinence-subtype-transition-disease-progression-1055312746) Minassian VA, Yan X, Pilzek AL, Platte R, Stewart WF. Int Urogynecol J. 29(8):1179-1185. doi: 10.1007/s00192-018-3596-4. Epub 2018 Mar 13. 2018 Aug 01 - Publication ### [The iceberg of health care utilization in women with urinary incontinence.](https://www.sutterhealth.org/research/publications/health-care-utilization-in-women-with-ui-is-low-1055312611) Minassian VA, Yan X, Lichtenfeld MJ, Sun H, Stewart WF. Int Urogynecol J. 23(8):1087-93. doi: 10.1007/s00192-012-1743-x. Epub 2012 Apr 12. 2012 Aug 01 - Publication ### [Clinical validation of the Bladder Health Survey for urinary incontinence in a population sample of women.](https://www.sutterhealth.org/research/publications/clinical-validation-of-bladder-health-survey-for-ui-1055312569) Minassian VA, Yan XS, Sun H, Platte RO, Stewart WF. Int Urogynecol J. 27(3):453-61. doi: 10.1007/s00192-015-2849-8. Epub 2015 Sep 19. 2016 Mar 01 - Publication ### [Predictors of care seeking in women with urinary incontinence.](https://www.sutterhealth.org/research/publications/predictors-of-care-in-women-with-urinary-incontinence-1055312738) Minassian VA, Yan X, Lichtenfeld MJ, Sun H, Stewart WF. Neurourol Urodyn. 31(4):470-4. doi: 10.1002/nau.22235. Epub 2012 Feb 29. 2012 Apr 01 [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]} ``` ```json {"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/publications/stress-vs-urgency-ui-and-effect-on-qol-1055312598#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Research publications","item":"https://www.sutterhealth.org/research/publications"},{"@type":"ListItem","position":4,"name":"Stress vs urgency UI and effect on QOL."}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalScholarlyArticle","@id":"https://www.sutterhealth.org/research/publications/stress-vs-urgency-ui-and-effect-on-qol-1055312598#medicalscholarlyarticle","name":"The interaction of stress and urgency urinary incontinence and its effect on quality of life.","headline":"Stress vs urgency UI and effect on QOL.","abstract":"INTRODUCTION AND HYPOTHESIS: The objective was to estimate the impact of stress and urgency urinary incontinence (UI) on the quality of life (QOL), and to determine whether the impact varies according to UI severity. METHODS: We used data from the General Longitudinal Overactive Bladder Evaluation-UI study in women. Stress and urgency UI symptom severity scores ranged from 0 to 8. We used logistic regression to test the relation among different severity levels of stress and urgency UI, and their interaction with the Incontinence Impact Questionnaire (IIQ-7). This was categorized according to percentage ranges as 0-40% (reference), 41-80%, and 81-100%. RESULTS: Both stress and urgency UI were significantly associated with IIQ-7. Higher scores had higher odds ratios (ORs). The OR for urgency vs stress UI was greater at the same severity level. For instance, comparing IIQ-7 quintiles (0-40% vs 41-80%), the OR for an association with an urgency UI score of 5-6 was 5.27 (95% CI = 3.78-7.33) vs 2.76 (95% CI = 2.07-3.68) for a stress UI score of 5-6. Both UI subtypes were more strongly related to the upper (81-100%) than the to the lower (41-80%) quintiles. There was a strong positive urgency UI and stress UI interaction with the upper (i.e., 81-100%) but not the two next lower (41-80%) quintiles. CONCLUSION: The impact of UI subtypes on QOL varies according to the score of IIQ-7, stress and urgency UI, and their interaction. Urgency vs stress UI has a stronger impact. The effect is greatest for high IIQ-7 scores with a significant share mediated by the interaction of the two UI subtypes.","description":"Estimate the impact of stress vs. urgency UI on QOL, and to determine whether the impact varies according to UI severity.","keywords":["Women's Health","Urologic Diseases"],"datePublished":"2015-02-01","url":"https://www.sutterhealth.org/research/publications/stress-vs-urgency-ui-and-effect-on-qol-1055312598","inLanguage":"en-US","identifier":[{"@type":"PropertyValue","propertyID":"PMID","value":"25278207"},{"@type":"PropertyValue","propertyID":"DOI","value":"10.1007/s00192-014-2505-8"}],"sameAs":["https://pubmed.ncbi.nlm.nih.gov/25278207/","https://doi.org/10.1007/s00192-014-2505-8"],"isPartOf":{"@type":"Periodical","name":"Int Urogynecol J"},"author":[{"@type":"Person","name":"Minassian VA"},{"@type":"Person","name":"Sun H"},{"@type":"Person","@id":"https://www.sutterhealth.org/research/investigators/xiaowei-sherry-yan-phd-1049681042","name":"Yan XS","url":"https://www.sutterhealth.org/research/investigators/xiaowei-sherry-yan-phd-1049681042"},{"@type":"Person","name":"Clarke DN"},{"@type":"Person","name":"Stewart WF"}],"sourceOrganization":{"@type":"MedicalOrganization","name":"Palo Alto Medical Foundation Research Institute"},"about":[{"@type":"DefinedTerm","name":"Women's Health","url":"https://www.sutterhealth.org/research-search-results?facets=%5B%7B%22i%22%3A%22c_researchTopics.name%22%2C%22v%22%3A%5B%22Women%27s+Health%22%5D%7D%5D&verticalKey=research_publication"},{"@type":"DefinedTerm","name":"Urologic Diseases","url":"https://www.sutterhealth.org/research-search-results?facets=%5B%7B%22i%22%3A%22c_researchTopics.name%22%2C%22v%22%3A%5B%22Urologic+Diseases%22%5D%7D%5D&verticalKey=research_publication"}],"mainEntityOfPage":{"@type":"WebPage","@id":"https://www.sutterhealth.org/research/publications/stress-vs-urgency-ui-and-effect-on-qol-1055312598","breadcrumb":{"@id":"https://www.sutterhealth.org/research/publications/stress-vs-urgency-ui-and-effect-on-qol-1055312598#breadcrumblist"}}} ```