--- title: "Baseline reach and adoption characteristics in a randomized controlled trial of two weight loss interventions translated into primary care: A structured report of real-world applicability | Sutter Health" description: "Using data from the E-LITE randomized controlled trial, we evaluated potential of its two DPP-based interventions to reach populations and be adopted into use." url: "https://www.sutterhealth.org/research/publications/weight-loss-interventions-translated-into-pc-1055312588" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Research publications](https://www.sutterhealth.org/research/publications) / 4. Baseline reach and adoption characteristics in a randomized controlled trial of two weight loss interventions translated into primary care: A structured report of real-world applicability # Baseline reach and adoption characteristics in a randomized controlled trial of two weight loss interventions translated into primary care: A structured report of real-world applicability Yank V, Stafford RS, Rosas LG, & Ma J. _Contemp Clin Trials. 34(1):126-35. doi: 10.1016/j.cct.2012.10.007. Epub 2012 Oct 31._ 2013-01-01 ## Abstract BACKGROUND: Although the Diabetes Prevention Program (DPP) lifestyle intervention reduced type 2 diabetes incidence by 58% among high-risk adults at academic centers, it requires translation into typical primary care settings. Using baseline data from the Evaluation of Lifestyle Interventions to Treat Elevated Cardiometabolic Risk in Primary Care (E-LITE) randomized controlled trial, we evaluated the potential of its two DPP-based interventions to reach their target populations and be adopted into routine use. METHODS: Overweight/obese adults with increased cardiometabolic risk enrolled from one primary care clinic. Using the RE-AIM (Reach, Effectiveness, Adoption, Implementation, Maintenance) model, we assessed reach with data on patient identification, participation, and representativeness, and adoption with data on intervention feasibility and potential for organizational diffusion. RESULTS: The target population was identified by searching electronic health records. Contact was attempted for 2391 patients who completed initial screening by phone (56% uptake) or online (44%). Most (88%) of those screened ineligible were not within the target population; 12% were excluded because of research requirements. Conservatively estimated participation rate was 44%. Participants (n=241) included 54% men and had a mean (SD) age of 52.9 years (10.6) and body mass index of 32 kg/m(2) (5.4). Regarding adoption, all clinic physicians agreed to participate. The feasibility of intervention implementation and dissemination was enhanced by leveraging existing intervention, training, and primary care resources. CONCLUSIONS: E-LITE's lifestyle interventions had fair-to-good potential for primary care reach and adoption. Our trial evidence and structured reporting may inform real-world implementation of translational trials by health networks, physicians, and payers. [PubMed abstract](http://www.ncbi.nlm.nih.gov/pubmed/?term=Baseline+reach+and+adoption+characteristics+in+a+randomized) ## Research topics - [Diabetes, Insulin Resistance and Metabolic Syndrome](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Diabetes%2C+Insulin+Resistance+and+Metabolic+Syndrome%5C%22%22) - [Disease Management](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Disease+Management%5C%22%22) - [Health Services](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Health+Services%5C%22%22) - [Obesity](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Obesity%5C%22%22) ## Related publications [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) - Publication ### [Short-term weight loss patterns, baseline predictors, and longer-term follow-up within a randomized controlled trial.](https://www.sutterhealth.org/research/publications/short-term-wt-loss-patterns-in-dpp-intervention-1055312751) Yank V, Xiao L, Wilson SR, Stafford RS, Rosas LG, Ma J. Obesity (Silver Spring). 22(1):45-51. doi: 10.1002/oby.20510. Epub 2013 Oct 15. 2014 Jan 01 - Publication ### [Two-year weight-loss maintenance in primary care-based Diabetes Prevention Program lifestyle interventions.](https://www.sutterhealth.org/research/publications/two-yr-wt-loss-maintenance-in-diabetes-program-1055312744) Xiao L, Yank V, Wilson SR, Lavori PW, Ma J. Nutr Diabetes. 3:e76. doi: 10.1038/nutd.2013.17. 2013 Jun 24 - Publication ### [Barriers and facilitators to real-world implementation of the Diabetes Prevention Program in large healthcare systems: lifestyle coach perspectives.](https://www.sutterhealth.org/research/publications/barriers-facilitators-diabetes-prev-program-implementation-1055312731) Halley MC, Petersen J, Nasrallah C, Szwerinski N, Romanelli R, Azar KMJ. J Gen Intern Med. doi: 10.1007/s11606-020-05744-y. \[Epub ahead of print\] 2020 Apr 06 - Publication ### [Translating an evidence-based lifestyle intervention program into primary care: lessons learned.](https://www.sutterhealth.org/research/publications/translate-lifestyle-program-in-primary-care-1055312592) Blonstein AC, Yank V, Stafford RS, Wilson SR, Rosas LG, Ma J. Health Promot Pract. 14(4):491-7. doi: 10.1177/1524839913481604. Epub 2013 Mar 28. 2013 Jul 01 - Publication ### [Comparative effectiveness of early versus delayed metformin in the treatment of type 2 diabetes.](https://www.sutterhealth.org/research/publications/early-vs-delayed-metformin-type-2-diabetes-1055312946) Romanelli RJ, Chung S, Pu J, Nimbal V, Zhao B, Palaniappan L. Diabetes Res Clin Pract. pii: S0168-8227(15)00046-7. doi: 10.1016/j.diabres.2014.12.019. \[Epub ahead of print\] 2015 Jan 21 [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]} ``` ```json {"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/publications/weight-loss-interventions-translated-into-pc-1055312588#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Research publications","item":"https://www.sutterhealth.org/research/publications"},{"@type":"ListItem","position":4,"name":"Baseline reach and adoption characteristics in a randomized controlled trial of two weight loss interventions translated into primary care: A structured report of real-world applicability"}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalScholarlyArticle","@id":"https://www.sutterhealth.org/research/publications/weight-loss-interventions-translated-into-pc-1055312588#medicalscholarlyarticle","name":"Baseline reach and adoption characteristics in a randomized controlled trial of two weight loss interventions translated into primary care: A structured report of real-world applicability","headline":"Baseline reach and adoption characteristics in a randomized controlled trial of two weight loss interventions translated into primary care: A structured report of real-world applicability","abstract":"BACKGROUND: Although the Diabetes Prevention Program (DPP) lifestyle intervention reduced type 2 diabetes incidence by 58% among high-risk adults at academic centers, it requires translation into typical primary care settings. Using baseline data from the Evaluation of Lifestyle Interventions to Treat Elevated Cardiometabolic Risk in Primary Care (E-LITE) randomized controlled trial, we evaluated the potential of its two DPP-based interventions to reach their target populations and be adopted into routine use. METHODS: Overweight/obese adults with increased cardiometabolic risk enrolled from one primary care clinic. Using the RE-AIM (Reach, Effectiveness, Adoption, Implementation, Maintenance) model, we assessed reach with data on patient identification, participation, and representativeness, and adoption with data on intervention feasibility and potential for organizational diffusion. RESULTS: The target population was identified by searching electronic health records. Contact was attempted for 2391 patients who completed initial screening by phone (56% uptake) or online (44%). Most (88%) of those screened ineligible were not within the target population; 12% were excluded because of research requirements. Conservatively estimated participation rate was 44%. Participants (n=241) included 54% men and had a mean (SD) age of 52.9 years (10.6) and body mass index of 32 kg/m(2) (5.4). Regarding adoption, all clinic physicians agreed to participate. The feasibility of intervention implementation and dissemination was enhanced by leveraging existing intervention, training, and primary care resources. CONCLUSIONS: E-LITE's lifestyle interventions had fair-to-good potential for primary care reach and adoption. 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