--- title: "Whole-heart coronary MR angiography. | Sutter Health" description: "Phyllotaxis 3D cones results in improved qualitative image scores & coronary vessel sharpness for whole-heart coronary magnetic resonance angiography." url: "https://www.sutterhealth.org/research/publications/whole-heart-coronary-mr-angiography-1055312405" --- 1. [Home](https://www.sutterhealth.org/) / 2. [Research](https://www.sutterhealth.org/research) / 3. [Research publications](https://www.sutterhealth.org/research/publications) / 4. Whole-heart coronary MR angiography. # Whole-heart coronary MR angiography using a 3D cones phyllotaxis trajectory. Malavé MO, Baron CA, Addy NO, Cheng JY, Yang PC, Hu BS, & Nishimura DG. _Magn Reson Med. doi: 10.1002/mrm.27475. \[Epub ahead of print\]_ 2018-10-29 ## Abstract PURPOSE: To develop a 3D cones steady-state free precession sequence with improved robustness to respiratory motion while mitigating eddy current artifacts for free-breathing whole-heart coronary magnetic resonance angiography. METHOD: The proposed sequence collects cone interleaves using a phyllotaxis pattern, which allows for more distributed k-space sampling for each heartbeat compared to a typical sequential collection pattern. A Fibonacci number of segments is chosen to minimize eddy current effects with the trade-off of an increased number of acquisition heartbeats. For verification, phyllotaxis-cones is compared to sequential-cones through simulations, phantom studies, and in vivo coronary scans with 8 subjects using 2D image-based navigators for retrospective motion correction. RESULTS: Simulated point spread functions and moving phantom results show less coherent motion artifacts for phyllotaxis-cones compared to sequential-cones. Assessment of the right and left coronary arteries using reader scores and the image edge profile acutance vessel sharpness metric indicate superior image quality and sharpness for phyllotaxis-cones. CONCLUSION: Phyllotaxis 3D cones results in improved qualitative image scores and coronary vessel sharpness for free-breathing whole-heart coronary magnetic resonance angiography compared to standard sequential ordering when using a steady-state free precession sequence. [PubMed abstract](https://www.ncbi.nlm.nih.gov/pubmed/30370941) ![Bob S Hu, M.D.](https://dyn.mktgcdn.com/p/OLtyV-80yDbOmh0GcQI3xnNzxEtgLP1RmJcZvvKP3u4/fit=crop,gravity=auto,dpr=2,width=188,height=250,quality=100) Bob S Hu, M.D. Principal investigator [View profile](https://www.sutterhealth.org/research/investigators/bob-s-hu-md-1049681033) ## Research topics - [Cardiovascular Diseases](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Cardiovascular+Diseases%5C%22%22) - [Disease Management](https://www.sutterhealth.org/research-search-results?query=%22%5C%22Disease+Management%5C%22%22) ## Related publications [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) - Publication ### [Nonrigid autofocus motion correction for coronary MR angiography with a 3D cones trajectory.](https://www.sutterhealth.org/research/publications/nonrigid-autofocus-motion-correctn-ht-mra-1055312469) Ingle RR, Wu HH, Addy NO, Cheng JY, Yang PC, Hu BS, Nishimura DG. Magn Reson Med. 72(2):347-61. doi: 10.1002/mrm.24924. Epub 2013 Sep 4. 2014 Aug 01 - Publication ### [Cardiovascular magnetic resonance phase contrast imaging.](https://www.sutterhealth.org/research/publications/cardiovasc-mri-phase-contrast-1055312458) Nayak KS, Nielsen JF, Bernstein MA, Markl M, D Gatehouse P, M Botnar R, Saloner D, Lorenz C, Wen H, S Hu B, Epstein FH, N Oshinski J, Raman SV. J Cardiovasc Magn Reson. 17(1):71. doi: 10.1186/s12968-015-0172-7. 2015 Aug 09 - Publication ### [Combined outer volume suppression and T2 preparation sequence for coronary angiography.](https://www.sutterhealth.org/research/publications/outer-vol-suppressn-t2-prepseq-ht-angiography-1055312448) Luo J, Addy NO, Ingle RR, Hargreaves BA, Hu BS, Nishimura DG, Shin T. Magn Reson Med. 74(6):1632-9. doi: 10.1002/mrm.25575. Epub 2014 Dec 17. 2015 Dec 01 - Publication ### [Mitral valve operations through standard and smaller incisions.](https://www.sutterhealth.org/research/publications/mitral-valve-operations-std-smaller-incisions-1055312446) Gaudiani VA, Grunkemeier GL, Castro LJ, Fisher AL, Wu Y. Heart Surg Forum. 7(4):E337-42. 2004 Jan 01 - Publication ### [Antiplatelet therapy use after discharge among acute myocardial infarction patients with in-hospital bleeding.](https://www.sutterhealth.org/research/publications/antiplatelet-tx-post-discharge-ami-pts-1055312976) Wang TY, Xiao L, Alexander KP, Rao SV, Kosiborod MN, Rumsfeld JS, Spertus JA, Peterson ED. Circulation. 118(21):2139-45. doi: 10.1161/CIRCULATIONAHA.108.787143. Epub 2008 Nov 3. 2008 Nov 18 [View all publications](https://www.sutterhealth.org/research-search-results?verticalKey=research_publication) ```json {"@context":"https://schema.org","@type":"MedicalOrganization","name":"Sutter Health","@id":"https://www.sutterhealth.org/#medicalorganization","url":"https://www.sutterhealth.org","logo":"https://www.sutterhealth.org/static/images/sutter-health-logo.svg","address":{"@type":"PostalAddress","streetAddress":"2200 River Plaza Drive","addressLocality":"Sacramento","addressRegion":"CA","postalCode":"95833","addressCountry":"US"},"areaServed":{"@type":"AdministrativeArea","name":"California"},"sameAs":["https://www.facebook.com/SutterHealth","https://www.instagram.com/sutterhealth/","https://x.com/SutterHealth","https://www.youtube.com/sutterhealth","https://www.linkedin.com/company/sutter-health","https://en.wikipedia.org/wiki/Sutter_Health"]} ``` ```json {"@context":"https://schema.org","@type":"BreadcrumbList","@id":"https://www.sutterhealth.org/research/publications/whole-heart-coronary-mr-angiography-1055312405#breadcrumblist","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.sutterhealth.org/"},{"@type":"ListItem","position":2,"name":"Research","item":"https://www.sutterhealth.org/research"},{"@type":"ListItem","position":3,"name":"Research publications","item":"https://www.sutterhealth.org/research/publications"},{"@type":"ListItem","position":4,"name":"Whole-heart coronary MR angiography."}]} ``` ```json {"@context":"https://schema.org","@type":"MedicalScholarlyArticle","@id":"https://www.sutterhealth.org/research/publications/whole-heart-coronary-mr-angiography-1055312405#medicalscholarlyarticle","name":"Whole-heart coronary MR angiography using a 3D cones phyllotaxis trajectory.","headline":"Whole-heart coronary MR angiography.","abstract":"PURPOSE: To develop a 3D cones steady-state free precession sequence with improved robustness to respiratory motion while mitigating eddy current artifacts for free-breathing whole-heart coronary magnetic resonance angiography. METHOD: The proposed sequence collects cone interleaves using a phyllotaxis pattern, which allows for more distributed k-space sampling for each heartbeat compared to a typical sequential collection pattern. A Fibonacci number of segments is chosen to minimize eddy current effects with the trade-off of an increased number of acquisition heartbeats. For verification, phyllotaxis-cones is compared to sequential-cones through simulations, phantom studies, and in vivo coronary scans with 8 subjects using 2D image-based navigators for retrospective motion correction. RESULTS: Simulated point spread functions and moving phantom results show less coherent motion artifacts for phyllotaxis-cones compared to sequential-cones. Assessment of the right and left coronary arteries using reader scores and the image edge profile acutance vessel sharpness metric indicate superior image quality and sharpness for phyllotaxis-cones. 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