Jump to content

Choose locationSutter Care at Home
  • Sign in or Enroll
    • Open I want to choose my medical group or hospital
    • Clear my location
Change Location
Sutter Health
  • Video Visits
  • Find Doctors
  • Find Locations
  • Treatments & Services
  • Locations
  • Sign in or Enroll
    • Video Visits
    • Find Doctors
    • Find Locations
    • Treatments & Services
    • COVID-19 Resources
    • Monkeypox Resources
    • Pay a Bill
    • Symptom Checker
    • Get Care Today
    • Health & Wellness
    • Classes & Events
    • Research & Clinical Trials
    • For Patients
    • About Sutter Health
    • Giving
    • Volunteering
    • Careers
    • News
    • For Medical Professionals
    • Other Business Services
Close Search
  • Home
  • Sutter Care at Home
  • Research
  • Child and Adolescent Health
Content

Interferon beta-1a in children with multiple sclerosis is well tolerated.

Description

Waubant E, Hietpas J, Stewart T, Dyme Z, Herbert J, Lacy J, Miller C, Rensel M, Schwid S, Goodkin D., Neuropediatrics. 32(4):211-3., 2001 Aug 01

Investigators

Joseph R. Lacy, M.D.

Abstract

BACKGROUND: Multiple sclerosis is a chronic demyelinating disease rare in children. Currently marketed disease modifying therapies are limited to adults.

OBJECTIVE: To determine the tolerability of interferon beta-1a (IFNB-1a) 30 mcg injected intramuscularly once a week in children with clinically definite relapsing-remitting multiple sclerosis (RRMS).

DESIGN/METHODS: A standardized questionnaire was sent to neurologists in the United States to determine the tolerability of IFNB-1a in patients younger than 16 years.

RESULTS: Tolerability data were available for 9 of 33 children who were reported to initiate IFNB-1a. Mean age on initiating treatment was 12.7 years (range 8 - 15) and mean duration of therapy was 17 months (range 5 - 36). No patient discontinued therapy due to an adverse event.

CONCLUSIONS: Preliminary data indicate that weekly intramuscular injections of IFNB-1a are well tolerated.

Pubmed Abstract

Pubmed AbstractOpens New Window

Associated Topics

  • Child and Adolescent Health
  • Disease Management
  • Neurological Disorders

Related Publications

Physical education policy compliance and Latino children's fitness: does the association vary by school neighborhood socioeconomic advantage?

Sanchez-Vaznaugh EV, Goldman Rosas L, Fernández-Peña JR, Baek J, Egerter S, Sánchez BN.
PLoS One. 12(6):e0178980. doi: 10.1371/journal.pone.0178980. eCollection 2017.
2017 Jun 07

Association between physician compensation methods and delivery of guideline-concordant STD care: is there a link?

Pourat N, Rice T, Tai-Seale M, Bolan G, Nihalani J.
Am J Manag Care. 11(7):426-32.
2005 Jul 01

Perceived appropriateness of shared decision-making in the emergency department: a survey study.

Probst MA, Kanzaria HK, Frosch DL, Hess EP, Winkel G, Ngai KM, Richardson LD.
Acad Emerg Med. 23(4):375-81. doi: 10.1111/acem.12904. Epub 2016 Mar 22.
2016 Apr 01

Does healthy diet matter in asthma prevention and control?

Jun M, Nan L.
Indian Pediatr. 52(1):19-20.
2015 Jan 01

Development of the adult and child complementary medicine questionnaires fielded on the National Health Interview Survey.

Stussman BJ, Bethell CD, Gray C, Nahin RL.
BMC Complement Altern Med. 13:328. doi: 10.1186/1472-6882-13-328.
2013 Nov 23
The Sutter Health Network of Care
Expertise to fit your needs
Primary Care

Check-ups, screenings and sick visits for adults and children.

Specialty Care

Expertise and advanced technologies in all areas of medicine.

Emergency Care

For serious accidents, injuries and conditions that require immediate medical care.

Urgent Care

After-hours, weekend and holiday services.

Walk-In Care

Convenient walk-in care clinics for your non-urgent health needs.

About Sutter

  • About Our Network
  • Annual Report
  • Awards
  • Community Benefit
  • Contact Us
  • News
  • Giving
  • Find Care

  • Birth Centers
  • Care Centers
  • Emergency Rooms
  • Hospitals
  • Imaging
  • Labs
  • Surgery Centers
  • Urgent Care
  • Walk-In Care
  • View All >
  • Featured Services

  • Behavioral Health
  • Cancer Services
  • Family Medicine
  • Home Health and Hospice
  • Orthopedics
  • Pediatrics
  • Pregnancy
  • Primary Care
  • Women's Health
  • View All >
  • Patient Resources

  • Accepted Health Plans
  • Classes and Events
  • Estimate Costs
  • Health and Wellness
  • Medical Records
  • Medicare Advantage
  • My Health Online
  • Pay a Bill
  • Symptom Checker
  • Our Team

  • For Employees
  • Physician Careers
  • Recruiting Events
  • Residencies and Fellowships
  • Sutter Careers
  • Vendors
  • Volunteers
    • ADA Accessibility
    • Contact
    • Privacy
    • Do Not Sell My Personal Information

    • LinkedIn Opens new window
    • YouTube Opens new window
    • Facebook Opens new window
    • Twitter Opens new window
    • Glassdoor Opens new window
    • Instagram Opens new window

    Copyright © 2022 Sutter Health. All rights reserved. Sutter Health is a registered trademark of Sutter Health ®, Reg. U.S. Patent & Trademark office.

    Cookie Policy

    We use cookies to give you the best possible user experience. By continuing to use the site, you agree to the use of cookies. Privacy Policy Cookie Preferences

    Privacy Policy Cookie Preferences