Jump to content

  • Set Your Location
  • Sign in or Enroll
Set Your LocationSutter Maternity & Surgery Center of Santa Cruz
  • Find a Doctor
  • Find a Location
  • Donate Now
  • Patient Login
    • Sign In to My Health Online
    • Enroll in My Health Online
    • Learn About My Health Online
    • Open Choose a medical group or hospital
    • Clear my location
Change Location
Sutter Health
  • BOOK APPOINTMENT
  • Book Appointment
  • Profile
Book Appointment
Walk-In Care

In-person care for minor illnesses.

Urgent Care

In-person care for moderate illnesses and injuries.

Video Visits

Virtual care with a Walk-In Care clinician.

Primary Care

Ongoing care and wellness for everyone.

COVID-19

Resources for vaccination and boosters.

Patient Login
  • Sign In to My Health Online
  • Enroll in My Health Online
  • Learn About My Health Online
  • Patients and Visitors

    Patients and Visitors

    Get personalized, coordinated care across Northern California through the Sutter network.

    View Patient Resources
    My Health Online

    Make appointments, message your doctor and more through our patient portal.

    Enroll Now
    • Find a DoctorFind a Doctor
    • Find a LocationFind a Location
    • View All ServicesView All Services
    • Request RecordsRequest Records
    • Pay a BillPay a Bill
    • Check SymptomsCheck Symptoms
    Patient Resources
    • Contact Us
    • Patient and Visitor Information
    • My Health Online Patient Portal
    • Classes and Events
    • Doctor Referrals
    • Health and Wellness
    • COVID-19 Vaccine Resources
    Billing and Insurance
    • Pay a Bill
    • Accepted Health Plans
    • Cost Estimates/Charges
    • Medicare Advantage
    • Sutter Health Plus
  • Treatments and Services

    Treatments and Services

    Access award-winning, comprehensive primary and specialty care for your whole family.

    View All Services
    Schedule a Visit

    Convenient care options for your everyday health needs.

    Book Appointment
    Get Care
    • Primary CarePrimary Care
    • Video VisitsVideo Visits
    • Walk-In CareWalk-In Care
    • Urgent CareUrgent Care
    • Emergency CareEmergency Care
    Featured Services
    • Mental Health
    • Pregnancy and Childbirth
    • Imaging
    • Pediatrics
    • Orthopedics
    • Cancer
    • Heart and Vascular
     
    • Dermatology
    • Physical Therapy
    • Ear, Nose, and Throat (ENT)
    • Labs
    • Urology
    • Neuroscience
    • Women's Health (OB/GYN)
    • View All Services
  • Research and Education

    Research and Education

    Our contributions to medical research and education lead to better healthcare outcomes.

    Research at Sutter
    Graduate Medical Education

    Join our robust training programs led by nationally known healthcare leaders.

    Explore Opportunities
    Research
    • Clinical TrialsClinical Trials
    • Research StudiesResearch Studies
    • PublicationsPublications
    • InvestigatorsInvestigators
    Education
    • Residencies and Fellowships
    • Continuing Medical Education
  • About Sutter

    About Us

    Explore the ways we provide innovative, compassionate care through our network.

    Learn About Sutter Health
    Work at Sutter Health

    Shape the future of healthcare and build your career within our diverse teams.

    Find Jobs
    About Sutter Health
    • About Us
    • Diversity and Inclusion
    • Awards and Honors
    • Leadership
    • Annual Report
    • News and Media
    • Patient Stories
    • Business Programs
    Community
    • Giving
    • Volunteer With Us
    • Community Benefit
    Careers
    • Jobs at Sutter
    • Physician Opportunities
    • Residencies and Fellowships
  • BOOK APPOINTMENTBook Appointment
Logo
  • Patients and Visitors
  • Treatments and Services
  • Research and Education
  • About Sutter
Find a DoctorFind a DoctorFind a LocationFind a LocationContact UsContact UsDonate NowDonate Now
BOOK APPOINTMENT
  • My Health Online Patient LoginMy Health Online Patient Login
  • Set My LocationSet My Location
Logo
  • Find a DoctorFind a Doctor
  • Find a LocationFind a Location
  • View All ServicesView All Services
  • Request RecordsRequest Records
  • Pay a BillPay a Bill
  • Check SymptomsCheck Symptoms
Patient Resources
  • Contact Us
  • Patient and Visitor Information
  • My Health Online Patient Portal
  • Classes and Events
  • Doctor Referrals
  • Health and Wellness
  • COVID-19 Vaccine Resources
Billing and Insurance
  • Pay a Bill
  • Accepted Health Plans
  • Cost Estimates/Charges
  • Medicare Advantage
  • Sutter Health Plus

Patients and Visitors

Get personalized, coordinated care across Northern California through the Sutter network.

View Patient Resources
My Health Online

Make appointments, message your doctor and more through our patient portal.

Enroll Now
Patient
My Health Online

Make appointments, message your doctor and more through our patient portal.

Enroll Now
Logo
Get Care
  • Primary CarePrimary Care
  • Video VisitsVideo Visits
  • Walk-In CareWalk-In Care
  • Urgent CareUrgent Care
  • Emergency CareEmergency Care
Featured Services
  • Mental Health
  • Pregnancy and Childbirth
  • Imaging
  • Pediatrics
  • Orthopedics
  • Cancer
  • Heart and Vascular
  • Dermatology
  • Physical Therapy
  • Ear, Nose, and Throat (ENT)
  • Labs
  • Urology
  • Neuroscience
  • Women's Health (OB/GYN)

Treatments and Services

Access award-winning, comprehensive primary and specialty care for your whole family.

View All Services
Schedule a Visit

Convenient care options for your everyday health needs.

Book Appointment
Logo
Research
  • Clinical TrialClinical Trials
  • Research StudiesResearch Studies
  • PublicationsPublications
  • InvestigatorsInvestigators
Education
  • Residencies and Fellowships
  • Continuing Medical Education

Research and Education

Our contributions to medical research and education lead to better healthcare outcomes.

Research at Sutter
Graduate Medical Education

Join our robust training programs led by nationally known healthcare leaders.

Explore Opportunities
Research
Graduate Medical Education

Join our robust training programs led by nationally known healthcare leaders.

Explore Opportunities
Logo
About Sutter Health
  • About Us
  • Diversity and Inclusion
  • Awards and Honors
  • Leadership
  • Annual Report
  • News and Media
  • Patient Stories
  • Business Programs
Community
  • Giving
  • Volunteer With Us
  • Community Benefit
Careers
  • Jobs at Sutter
  • Physician Opportunities
  • Residencies and Fellowships

About Us

Explore the ways we provide innovative, compassionate care through our network.

Learn About Sutter Health
Work at Sutter Health

Shape the future of healthcare and build your career within our diverse teams.

Find Jobs
Career
Work at Sutter Health

Shape the future of healthcare and build your career within our diverse teams.

Find Jobs
  • Home
  • Sutter Maternity & Surgery Center
  • Research
  • Cardiovascular Diseases
Content

Thoracic aorta calcification and noncardiovascular disease-related mortality: the multi-ethnic study of atherosclerosis.

Description

Thomas IC, Thompson CA, Yang M, Allison MA, Forbang NI, Michos ED, McClelland RL, Budoff MJ, Criqui MH., Arterioscler Thromb Vasc Biol. pii: ATVBAHA.118.310850. doi: 10.1161/ATVBAHA.118.310850. [Epub ahead of print], 2018 Jun 28

Abstract

OBJECTIVE: Arterial calcification is highly correlated with underlying atherosclerosis. Arterial calcification of the thoracic aorta is evident in many older individuals at high susceptibility to aging-related diseases and non-cardiovascular disease (CVD)-related mortality. In this study, we evaluated the association of thoracic aorta calcification (TAC) with non-CVD morbidity and mortality.

APPROACH AND RESULTS: We analyzed data from participants in the Multi-Ethnic Study of Atherosclerosis, a prospective cohort study of subclinical atherosclerosis, in which participants underwent cardiac computed tomography at baseline and were followed longitudinally for incident CVD events and non-CVD events. Using modified proportional hazards models accounting for the competing risk of CVD death and controlling for demographics, CVD risk factors, coronary artery calcium, and CVD events, we evaluated whether TAC was independently associated with non-CVD morbidity and mortality. Among 6765 participants (mean age, 62 years), 704 non-CVD deaths occurred for a median follow-up of 12.2 years. Compared with no TAC, the highest tertile of TAC volume was associated with a higher risk of non-CVD mortality (hazard ratio, 1.56; 95% confidence interval, 1.23-1.97), as well as several non-CVD diagnoses, including hip fracture (2.14; 1.03-4.46), chronic obstructive pulmonary disease (2.06; 1.29-3.29), and pneumonia (1.79; 1.30-2.45), with magnitudes of association that were larger than for those of coronary artery calcium.

CONCLUSIONS: TAC is associated with non-CVD morbidity and non-CVD mortality, potentially through a pathway that is unrelated to atherosclerosis. TAC may be a general marker of biological aging and an indicator of increased risk of non-CVD and death.

Pubmed Abstract

Pubmed AbstractOpens New Window

Associated Topics

  • Aging and Longevity
  • Cardiovascular Diseases
  • Health Disparities
  • Lung Diseases
  • Musculoskeletal Disorders

Related Publications

Medication burden in patients with acute coronary syndromes.

Wright EA, Steinhubl SR, Jones JB, Barua P, Yan X, Van Loan R, Frederick G, Bhandary D, Cobden D.
Am J Manag Care. 2017 Apr 1;23(4):e106-e112.
2017 Apr 01

A randomized telephone intervention trial to reduce primary medication nonadherence.

Fischer MA, Jones JB, Wright E, Van Loan RP, Xie J, Gallagher L, Wurst AM, Shrank WH.
J Manag Care Spec Pharm. 21(2):124-31.
2015 Feb 01

The relative efficacy and safety of clopidogrel in women and men a sex-specific collaborative meta-analysis.

Berger JS, Bhatt DL, Cannon CP, Chen Z, Jiang L, Jones JB, Mehta SR, Sabatine MS, Steinhubl SR, Topol EJ, Berger PB.
J Am Coll Cardiol. 54(21):1935-45. doi: 10.1016/j.jacc.2009.05.074.
2009 Nov 17

Effect of financial incentives to physicians, patients, or both on lipid levels: a randomized clinical trial.

Asch DA, Troxel AB, Stewart WF, Sequist TD, Jones JB, Hirsch AG, Hoffer K, Zhu J, Wang W, Hodlofski A, Frasch AB, Weiner MG, Finnerty DD, Rosenthal MB, Gangemi K, Volpp KG.
JAMA. 314(18):1926-35. doi: 10.1001/jama.2015.14850.
2015 Nov 10

The wired patient: patterns of electronic patient portal use among patients with cardiac disease or diabetes.

Jones JB, Weiner JP, Shah NR, Stewart WF.
J Med Internet Res. 17(2):e42. doi: 10.2196/jmir.3157.
2015 Feb 20
The Sutter Health Network of Care
Expertise to fit your needs
Primary Care

Check-ups, screenings and sick visits for adults and children.

Specialty Care

Expertise and advanced technologies in all areas of medicine.

Emergency Care

For serious accidents, injuries and conditions that require immediate medical care.

Urgent Care

After-hours, weekend and holiday services.

Walk-In Care

Convenient walk-in care clinics for your non-urgent health needs.

  • Contact Us
  • Find Doctors
  • Find Locations
  • Book Appointment
  • Request Medical Records
  • Donate Now
Sign in to My Health Online

Billing and Insurance

  • Pay a Bill
  • Accepted Health Plans
  • Estimate Costs
  • Medicare Advantage

About Sutter

  • About Our Network
  • Community Benefit
  • Annual Report
  • News and Media

Our Team

  • For Employees
  • For Medical Professionals
  • For Vendors
  • For Volunteers

Careers

  • Jobs at Sutter
  • Physician Jobs
  • Graduate Medical Education

Copyright © 2023 Sutter Health. All rights reserved. Sutter Health is a registered trademark of Sutter Health ®, Reg. U.S. Patent & Trademark office.

  • ADA Accessibility
  • Privacy
  • Do Not Sell My Personal Information
  • LinkedIn Opens new window
  • YouTube Opens new window
  • Facebook Opens new window
  • Twitter Opens new window
  • Instagram Opens new window
  • Glassdoor Opens new window

Cookie Policy

We use cookies to give you the best possible user experience. By continuing to use the site, you agree to the use of cookies. Privacy Policy Cookie Preferences

Privacy Policy Cookie Preferences