Study Information
Status: Active, Recruiting
Study Details
View study details on clinicaltrials.gov.
Locations
Greater Sacramento Valley
Clinical Trial FAQs
Information for patients and study volunteers, including frequently asked questions.
Description
This is a multicenter, randomized, double-blind, placebo-controlled study of niraparib plus pembrolizumab versus placebo plus pembrolizumab as maintenance therapy in participants with advanced or metastatic non-small cell lung cancer (NSCLC) who have achieved stable disease (SD), partial response (PR), or complete response (CR) following completion of standard of care first-line platinum-based induction chemotherapy with pembrolizumab. The primary hypotheses are: participants with confirmed diagnosis of NSCLC could benefit from niraparib plus pembrolizumab versus placebo plus pembrolizumab with respect to Progression-free survival (PFS) and Overall survival (OS).
Principal Investigator
Co-Investigator(s)
Jaspreet K Dhillon, Medical Oncologist, Vijay Suhag, M.D., Kristin N. Arreola, M.D., Rajeswari Chellappah, M.D., Sivakumar Reddy, M.D., Brian K. Kim, M.D, Kristie A. Bobolis, M.D.
Related Studies
The Impact of Smoking, Comorbidities, and Race/Ethnicity on COVID-19 Infection and Disease Severity
Using EHR from a large healthcare system in Northern CA, we will study the impact of smoking, comorbidities, race on COVID-19 infection and disease severity.
Investigator: Jiang Li, Ph.D., MPH