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  • Lung Cancer
Content

Locally Advanced (ZEAL-1L GlaxoSmithKline 213400)

Study Information

Status: Active, Recruiting

Study Details

View study details on clinicaltrials.gov.

Locations

Greater Sacramento Valley

Clinical Trial FAQs

Information for patients and study volunteers, including frequently asked questions.

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Description

This is a multicenter, randomized, double-blind, placebo-controlled study of niraparib plus pembrolizumab versus placebo plus pembrolizumab as maintenance therapy in participants with advanced or metastatic non-small cell lung cancer (NSCLC) who have achieved stable disease (SD), partial response (PR), or complete response (CR) following completion of standard of care first-line platinum-based induction chemotherapy with pembrolizumab. The primary hypotheses are: participants with confirmed diagnosis of NSCLC could benefit from niraparib plus pembrolizumab versus placebo plus pembrolizumab with respect to Progression-free survival (PFS) and Overall survival (OS).

Principal Investigator

Deepti Behl, MD

Co-Investigator(s)

Rajeswari Chellappah, M.D., Kristie A. Bobolis, M.D., Brian K. Kim, M.D, Sivakumar Reddy, M.D., Jaspreet K Dhillon, Medical Oncologist, Vijay Suhag, M.D., Kristin N. Arreola, M.D. 

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Investigator: Jiang Li, Ph.D., MPH 

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