Hepatology researchers are investigating the cellular and molecular mechanisms underlying hepatitis B, C and other liver diseases. Identifying early molecular or genetic changes - which may be detected before the disease manifests any clinical symptoms - could lead to interventions that reduce the severity of liver disease, or even prevent it from developing. Clinical researchers in the Liver Disease Management and Transplant Program are leading new investigations into hepatitis B and C disease management, hepatoma, hepatitis and HIV co-infection, nonalcoholic steatohepatitis, hepatorenal syndrome, and the care of liver transplant patients.